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References
Antonny B, Huber I, Paris S, Chabre M, Cassel D. Activation of ADP-ribosylation factor 1 GTPase-activating protein by phosphatidylcholine-derived diacylglycerols. J Biol Chem. 1997;272:30848–51.
Bigay J, Casella JF, Drin G, Mesmin B, Antonny B. ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif. EMBO J. 2005;24:2244–53.
Cukierman E, Huber I, Rotman M, Cassel D. The ARF1 GTPase-activating protein: zinc finger motif and Golgi complex localization. Science. 1995;270:1999–2002.
Drin G, Morello V, Casella JF, Gounon P, Antonny B. Asymmetric tethering of flat and curved lipid membranes by a golgin. Science. 2008;320:670–3.
Goldberg J. Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis. Cell. 1999;96:893–902.
Huber I, Cukierman E, Rotman M, Aoe T, Hsu VW, Cassel D. Requirement for both the amino-terminal catalytic domain and a noncatalytic domain for in vivo activity of ADP-ribosylation factor GTPase-activating protein. J Biol Chem. 1998;273:24786–91.
Kartberg F, Asp L, Dejgaard SY, Smedh M, Fernandez-Rodriguez J, Nilsson T, Presley JF. ARFGAP2 and ARFGAP3 are essential for COPI coat assembly on the Golgi membrane of living cells. J Biol Chem. 2010;285:36709–20.
Lanoix J, Ouwendijk J, Lin CC, Stark A, Love HD, Ostermann J, Nilsson T. GTP hydrolysis by arf-1 mediates sorting and concentration of Golgi resident enzymes into functional COP I vesicles. EMBO J. 1999;18:4935–48.
Lee SY, Yang JS, Hong W, Premont RT, Hsu VW. ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation. J Cell Biol. 2005;168:281–90.
Levi S, Rawet M, Kliouchnikov L, Parnis A, Cassel D. Topology of amphipathic motifs mediating Golgi localization in ArfGAP1 and its splice isoforms. J Biol Chem. 2008;283:8564–72.
Luo R, Randazzo PA. Kinetic analysis of Arf GAP1 indicates a regulatory role for coatomer. J Biol Chem. 2008;283:21965–77.
Makler V, Cukierman E, Rotman M, Admon A, Cassel D. ADP-ribosylation factor-directed GTPase-activating protein. Purification and partial characterization. J Biol Chem. 1995;270:5232–7.
Mesmin B, Drin G, Levi S, Rawet M, Cassel D, Bigay J, Antonny B. Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature. Biochemistry. 2007;46:1779–90.
Nickel W, Malsam J, Gorgas K, Ravazzola M, Jenne N, Helms JB, Wieland FT. Uptake by COPI-coated vesicles of both anterograde and retrograde cargo is inhibited by GTPgammaS in vitro. J Cell Sci. 1998;111:3081–90.
Parnis A, Rawet M, Regev L, Barkan B, Rotman M, Gaitner M, Cassel D. Golgi localization determinants in ArfGAP1 and in new tissue-specific ArfGAP1 isoforms. J Biol Chem. 2006;281:3785–92.
Pepperkok R, Whitney JA, Gomez M, Kreis TECOPI. vesicles accumulating in the presence of a GTP restricted arf1 mutant are depleted of anterograde and retrograde cargo. J Cell Sci. 2000;113:135–44.
Poon PP, Cassel D, Spang A, Rotman M, Pick E, Singer RA, Johnston GC. Retrograde transport from the yeast Golgi is mediated by two ARF GAP proteins with overlapping function. EMBO J. 1999;18:555–64.
Serafini T, Orci L, Amherdt M, Brunner M, Kahn RA, Rothman JE. ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell. 1991;67:239–53.
Szafer E, Pick E, Rotman M, Zuck S, Huber I, Cassel D. Role of coatomer and phospholipids in GTPase-activating protein-dependent hydrolysis of GTP by ADP-ribosylation factor-1. J Biol Chem. 2000;275:23615–9.
Szafer E, Rotman M, Cassel D. Regulation of GTP hydrolysis on ADP-ribosylation factor-1 at the Golgi membrane. J Biol Chem. 2001;276:47834–9.
Tanigawa G, Orci L, Amherdt M, Ravazzola M, Helms JB, Rothman JE. Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles. J Cell Biol. 1993;123:1365–71.
Yang JS, Zhang L, Lee SY, Gad H, Luini A, Hsu VW. Key components of the fission machinery are interchangeable. Nat Cell Biol. 2006;8:1376–82.
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Rawet-Slobodkin, M. (2018). ArfGAP1. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_86
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DOI: https://doi.org/10.1007/978-3-319-67199-4_86
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