Skip to main content

Myosins

  • Reference work entry
  • First Online:
Encyclopedia of Signaling Molecules
  • 225 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 4,499.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 4,499.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Adelman MR, Taylor EW. Isolation of an actomyosin-like protein complex from slime mold plasmodium and the separation of the complex into actin- and myosin-like fractions. Biochemistry. 1969;8(12):4964–75.

    Article  CAS  PubMed  Google Scholar 

  • Bähler M. Class IX myosins. Protein Cell Regul. 2008;7:391–401.

    Article  Google Scholar 

  • Bahloul A, Chevreux G, Wells AL, Martin D, Nolt J, Yang Z, et al. The unique insert in myosin VI is a structural calcium-calmodulin binding site. Proc Natl Acad Sci U S A. 2004;101(14):4787–92.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Bement WM, Mooseker MS. TEDS rule: a molecular rationale for differential regulation of myosins by phosphorylation of the heavy chain head. Cell Motil Cytoskeleton. 1995;31(2):87–92.

    Article  CAS  PubMed  Google Scholar 

  • Boger ET, Frolenkov GI, Friedman TB, Belyantseva IA. Myosin XVA. Protein Cell Regul. 2008;7:441–67.

    Article  CAS  Google Scholar 

  • Brzeska H, Korn ED. Regulation of class I and class II myosins by heavy chain phosphorylation. J Biol Chem. 1996;271(29):16983–6.

    Article  CAS  PubMed  Google Scholar 

  • Buss F, Kendrick-Jones J. Myosin VI: a multifunctional motor protein. Protein Cell Regul. 2008;7:325–52.

    Article  CAS  Google Scholar 

  • Coluccio LM. Protein. Protein Cell Regul. 2008;7:95–124.

    Article  CAS  Google Scholar 

  • Coluccio LM, Geeves MA. Transient kinetic analysis of the 130-kDa myosin I (myr 1 gene product) from rat liver: a myosin I designed for maintenance of tension? J Biol Chem. 1999;274:21575–80.

    Article  CAS  PubMed  Google Scholar 

  • Conti MA, Kawamoto S, Adelstein RS. Non-muscle myosin II. Protein Cell Regul. 2008;7:223–64.

    Article  CAS  Google Scholar 

  • Cremo CR, Hartshorne DJ. Smooth-muscle myosin II. Protein Cell Regul. 2008;7:171–222.

    Article  CAS  Google Scholar 

  • Cyr JL, Dumont RA, Gillespie PG. Myosin-1c interacts with hair-cell receptors through its calmodulin-binding IQ domains. J Neurosci. 2002;22(7):2487–95.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • El-Amraoui A, Bahloul A, Petit C. Myosin VII. Protein Cell Regul. 2008;7:353–73.

    Article  CAS  Google Scholar 

  • El-Mezgueldi M, Bagshaw CR. The myosin family: biochemical and kientic properties. Protein. Cell Regul. 2008;7:55–93.

    CAS  Google Scholar 

  • Holmes KC. Myosin structure. In: Coluccio LM, editor. Myosins: a superfamily of molecular motors. Dordrecht: Springer; 2008. p. 35–54.

    Google Scholar 

  • Ito K, Ikebe M, Kashiyama T, Mogami T, Kon T, Yamamoto K. Kinetic mechanism of the fastest motor protein, Chara myosin. J Biol Chem. 2007;282(27):19534–45.

    Article  CAS  PubMed  Google Scholar 

  • Kambara T, Komaba S, Ikebe M. Human myosin III is a motor having an extremely high affinity for actin. J Biol Chem. 2006;281(49):37291–301.

    Article  CAS  PubMed  Google Scholar 

  • Knecht DA, Loomis WF. Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum. Science. 1987;236(4805):1081–6.

    Article  CAS  PubMed  Google Scholar 

  • Laakso JM, Lewis JH, Shuman H, Ostap EM. Myosin I can act as a molecular force sensor. Science. 2008;321(5885):133–6.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Mooseker MS, Foth BJ. The structural and functional diversity of the myosin family. Protein Cell Regul. 2008;7:1–34. (Myosins: a superfamily of molecular motors [L.M. Coluccio, ed.]).

    CAS  Google Scholar 

  • Nambiar R, McConnell RE, Tyska MJ. Control of cell membrane tension by myosin-I. Proc Natl Acad Sci U S A. 2009;106(29):11972–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Odronitz F, Kollmar M. Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species. Genome Biol. 2007;8(9):R196.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Phichith D, Travaglia M, Yang Z, Liu X, Zong AB, Safer D, et al. Cargo binding induces dimerization of myosin VI. Proc Natl Acad Sci U S A. 2009;106(41):17320–4.

    Article  PubMed  PubMed Central  Google Scholar 

  • Pollard TD, Korn ED. Acanthamoeba myosin. I. Isolation from Acanthamoeba castellanii of an enzyme similar to muscle myosin. J Biol Chem. 1973;248(13):4682–90.

    CAS  PubMed  Google Scholar 

  • Reggiani C, Bottinelli R. Myosin II: sarcomeric myosins, the motors of contraction in cardiac and skeletal muscles. Protein Cell Regul. 2008;7:125–70. (Myosins: a superfamily of molecular motors [L.M. Coluccio, ed.]).

    Article  CAS  Google Scholar 

  • Salles FT, Merritt JRC, Manor U, Dougherty GW, Sousa AD, Moore JE, et al. Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments. Nat Cell Biol. 2009;11:443–50.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Sellers JR, Weisman LS, Myosin V. Protein. Cell Regul. 2008;7:289–323.

    CAS  Google Scholar 

  • Sun Y, Schroeder III HW, Beausang JF, Homma K, Ikebe M, Goldman YE. Myosin VI walks “wiggly” on actin with large and variable tilting. Mol Cell. 2007;28(6):954–64.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Sweeney HL, Houdusse A. Structural and functional insights into the myosin motor mechanism. Annu Rev Biophys. 2010;39:539–57.

    Article  CAS  PubMed  Google Scholar 

  • Szent-Györgyi AG. The early history of the biochemistry of muscle contraction. J Gen Physiol. 2004;123:631–41.

    Article  PubMed  PubMed Central  Google Scholar 

  • Tokuo H, Ikebe M. Myosin X transports Mena/VASP to the tip of filopodia. Biochem Biophys Res Commun. 2004;319(1):214–20.

    Article  CAS  PubMed  Google Scholar 

  • Veigel C, Coluccio LM, Jontes JD, Sparrow JC, Milligan RA, Molloy JE. The motor protein myosin-I produces its working stroke in two steps [see comments]. Nature. 1999;398(6727):530–3.

    Article  CAS  PubMed  Google Scholar 

  • Wang F, Thirumurugan K, Stafford WF, Hammer 3rd JA, Knight PJ, Sellers JR. Regulated conformation of myosin V. J Biol Chem 2004;279(4):2333–2336.

    Article  PubMed  CAS  Google Scholar 

  • Yang Y, Baboolal TG, Siththanandan V, Chen M, Walker ML, Knight PJ, et al. A FERM domain autoregulates Drosophila myosin 7a activity. Proc Natl Acad Sci U S A. 2009;106(11):4189–41894.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lynne M. Coluccio .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Coluccio, L.M. (2018). Myosins. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_530

Download citation

Publish with us

Policies and ethics