Skip to main content

VDR, the Vitamin D Receptor

  • Reference work entry
  • First Online:
Book cover Encyclopedia of Signaling Molecules

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 4,499.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 4,499.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Abbas AK, Lichtman AH, Pillai S. Cellular and molecular immunology. 6th ed. Oxford, UK: Elsevier; 2007.

    Google Scholar 

  • Baeke F, Takiishi T, Korf H, Gysemans C, Mathieu C. Vitamin D, modulator of the immune system. Curr Opin Pharmacol. 2010;10:482–96.

    Article  CAS  PubMed  Google Scholar 

  • Bikle DD. Nonclassic actions of vitamin D. J Clin Endocrinol Metab. 2009;94:26–34.

    Article  CAS  PubMed  Google Scholar 

  • Bikle DD. Vitamin D, an ancient hormone. Exp Dermatol. 2011;20:7–13.

    Article  CAS  PubMed  Google Scholar 

  • Bouillon R, Carmeliet G, Verlinden L, van Etten E, Verstuyf A, Luderer HF, Lieben L, Mathieu C, Demay M. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev. 2008;29:726–76.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. Am J Physiol Renal Physiol. 2005;289:F8–28.

    Article  CAS  PubMed  Google Scholar 

  • Feldman D, Pike JW, Glorieux FH. Vitamin D. 2nd ed. San Diego: Elsevier; 2005.

    Google Scholar 

  • Guillot X, Semerano L, Saidenberg-Kermanac’h N, Falgarone G, Boissier MC. Vitamin D and inflammation. Joint Bone Spine. 2010;77:552–7.

    Article  CAS  PubMed  Google Scholar 

  • Hendrickson WK, Flavin R, Kasperzyk JL, Fiorentino M, Fang F, Lis R, Fiore C, Penney KL, Ma J, Kantoff PW, Stampfer MJ, Loda M, Mucci LA, Giovannucci E. Vitamin D receptor protein expression in tumor tissue and prostate cancer progression. J Clin Oncol. 2011;29:2378–85.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Hochberg Z, Templeton AR. Evolutionary perspective in skin color, vitamin D and its receptor. Hormones. 2010;9:307–11.

    Article  PubMed  Google Scholar 

  • Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004;80:1678S–8.

    Article  CAS  PubMed  Google Scholar 

  • Jones G, Strugnell SA, DeLuca HF. Current understanding of the molecular actions of vitamin D. Physiol Rev. 1998;78:1193–231.

    Article  CAS  PubMed  Google Scholar 

  • Lacey DL, Axelrod J, Chappel JC, Kahn AJ, Teitelbaum SL. Vitamin D affects proliferation of a murine T helper cell clone. J Immunol. 1987;138:1680–6.

    CAS  PubMed  Google Scholar 

  • Lopez N, Sousa B, Martins D, Gomes M, Vieira D, Veronese LA, Milanezi F, Paredes J, Costa JL, Schmitt F. Alterations in vitamin D signaling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions vitamin D pathways unbalanced in breast lesions. BMC Cancer. 2010;10:483–95.

    Article  CAS  Google Scholar 

  • Luong KVQ, Nguyen LTH. The beneficial role of vitamin D and its analogs in cancer treatment and prevention. Crit Rev Oncol/Hematol. 2010;73:192–201.

    Article  Google Scholar 

  • Malloy PJ, Feldman D. Genetic disorders and defects in vitamin D action. Endocrinol Metab Clin N Am. 2010;39:333–46.

    Article  CAS  Google Scholar 

  • Nagpal S, Na S, Rathnachalam R. Noncalcemic actions of vitamin D receptor ligands. Endocr Rev. 2005;26:662–87.

    Article  CAS  PubMed  Google Scholar 

  • Plum LA, DeLuca HF. Vitamin D, disease and therapeutic opportunities. Nat Rev Drug Discov. 2010;9(12):941–55. doi:10.1038/nrd3318.

    Article  CAS  PubMed  Google Scholar 

  • van Etten E, Mathieu C. Immunoregulation by 1,25-dihydroxyvitamin D2:basic concepts. J Steroid Biochem Mol Biol. 2005;97:93–101.

    Article  CAS  PubMed  Google Scholar 

  • von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, Geisler C. Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat Immunol. 2010;11:344–9.

    Article  CAS  Google Scholar 

  • Yee YK, Chintalacharuvu SR, Lu J, Nagpal S. Vitamin D receptor modulators for inflammation and cancer. Mini Rev Med Chem. 2005;5:761–78.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Marina Rode von Essen or Carsten Geisler .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

von Essen, M.R., Geisler, C. (2018). VDR, the Vitamin D Receptor. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_287

Download citation

Publish with us

Policies and ethics