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Plasma Membrane Calcium-Transporting ATPase

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References

  • Axelsen KB, Palmgren MG. Evolution of substrate specificities in the P-type ATPase superfamily. J Mol Evol. 1998;46:84–101.

    Article  CAS  PubMed  Google Scholar 

  • Brini M, Carafoli E. Calcium pumps in health and disease. Physiol Rev. 2009;89:1341–78.

    Article  CAS  PubMed  Google Scholar 

  • Brini M, Carafoli E, Cali T. The plasma membrane calcium pumps: focus on the role in (neuro) pathology. Biochem Biophys Res Commun. 2016; pii: S0006-291X(16)31239-6. doi: 10.1016/j.bbrc.2016.07.117. Available online 29 July 2016.

    Article  PubMed  CAS  Google Scholar 

  • Hill JK, Williams DE, LeMasurier M, Dumont RA, Strehler EE, Gillespie PG. Splice-site A choice targets plasma-membrane Ca2+-ATPase isoform 2 to hair bundles. J Neurosci. 2006;26:6172–80.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Holton ML, Wang W, Emerson M, Neyses L, Armesilla AL. Plasma membrane calcium ATPase proteins as novel regulators of signal transduction pathways. World J rBiol Chem. 2010;1:201–8.

    Article  Google Scholar 

  • Huang H, Nagaraja RY, Garside ML, Akemann W, Knöpfel T, Empson RM. Contribution of plasma membrane Ca2+ ATPase to cerebellar synapse function. World J Biol Chem. 2010;1:95–102.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lehotsky J, Kaplán P, Murín R, Raeymaekers L. The role of plasma membrane Ca2+ pumps (PMCAs) in pathologies of mammalian cells. Front Biosci. 2002;7:d53–84.

    PubMed  CAS  Google Scholar 

  • Li M, Ho PW-L, Pang SY-Y, Tse ZH-M, Kung MH-W, Sham P-C, Ho S-L. PMCA4 (ATP2B4) mutation in familial spastic paraplegia. PLoS One. 2014;9:e104790.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Moeller JV, Olesen C, Winther A-ML, Nissen P. The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-omotioc pump. Q Rev Biophys. 2010;43:501–66.

    Article  CAS  Google Scholar 

  • Niggli V, Penniston JT, Carafoli E. Purification of the (Ca2+ + Mg2+)-ATPase from human erythrocyte membranes using a calmodulin affinity column. J Biol Chem. 1979;254:9955–8.

    PubMed  CAS  Google Scholar 

  • Oceandy D, Mohamed TMA, Cartwright EJ, Neyses L. Local signals with global impacts and clnical implications: lessons from the plasma membrane calcium pump (PMCA4). Biochim Biophys Acta. 2011;1813:974–8.

    Article  CAS  PubMed  Google Scholar 

  • Pászty K, Caride AJ, Bajzer Z, Offord CP, Padányi R, Hegedüs L, Varga K, Strehler EE, Enyedi A. Plasma membrane Ca2+-ATPases can shape the pattern of Ca2+ transients induced by store-operated Ca2+ entry. Sci Signal. 2015;8:ra19.

    Article  CAS  PubMed  Google Scholar 

  • Pedersen PL, Carafoli E. Ion motive ATPases. I. Ubiquity, properties, and significance for cell function. Trends Biochem Sci. 1987;12:146–50.

    Article  CAS  Google Scholar 

  • Prasad V, Okunade G, Liu L, Paul RJ, Shull GE. Distinct phenotypes among plasma membrane Ca2+-ATPase knockout mice. Ann N Y Acad Sci. 2007;1099:276–86.

    Article  CAS  PubMed  Google Scholar 

  • Reinhardt TA, Lippolis JD, Shull GE, Horst RL. Null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2 impairs calcium transport into milk. J Biol Chem. 2004;279:42369–73.

    Article  CAS  PubMed  Google Scholar 

  • Schatzmann HJ. ATP-dependent Ca++ extrusion from human red cells. Experientia. 1966;22:364–8.

    Article  CAS  PubMed  Google Scholar 

  • Strehler EE, Zacharias DA. Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps. Physiol Rev. 2001;81:21–50.

    Article  CAS  PubMed  Google Scholar 

  • Strehler EE, Caride AJ, Filoteo AG, Xiong Y, Penniston JT, Enyedi A. Plasma membrane Ca2+ ATPases as dynamic regulators of cellular calcium handling. Ann NY Acad Sci. 2007;1099:226–36.

    Article  CAS  PubMed  Google Scholar 

  • Strehler EE. The ATP2B plasma membrane Ca2+ ATPase family: regulation in response to changing demands of cellular calcium transport. In: Chakraborti S, Dhalla NS, editors. Regulation of Ca2+-ATPases, V-ATPases and F-ATPases, Advances in Biochemistry in Health and Disease14 Cham: Springer; 2016. p. 63–80.

    Chapter  Google Scholar 

  • Thever MD, Saier MH. Bioinformatic characterization of P-type ATPases encoded within the fully sequenced genomes of 26 eukaryotes. J Membr Biol. 2009;229:115–30.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Toyoshima C. How Ca2+-ATPase pumps ions across the sarcoplasmic reticulum membrane. Biochim Biophys Acta. 2009;1793:941–6.

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Emanuel E. Strehler .

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Strehler, E.E. (2018). Plasma Membrane Calcium-Transporting ATPase. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_133

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