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Matrix Metalloproteinases

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References

  • Bergers G, Brekken R, et al. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol. 2000;2(10):737–44.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Brkic M, Balusu S, et al. Friends or foes: matrix metalloproteinases and their multifaceted roles in neurodegenerative diseases. Mediat Inflamm. 2015;2015:620581.

    Article  CAS  Google Scholar 

  • Burrage PS, Mix KS, et al. Matrix metalloproteinases: role in arthritis. Front Biosci. 2006;11:529–43.

    Article  CAS  PubMed  Google Scholar 

  • Churg A, Zhou S, et al. Series “matrix metalloproteinases in lung health and disease”: matrix metalloproteinases in COPD. Eur Respir J. 2012;39(1):197–209.

    Article  CAS  PubMed  Google Scholar 

  • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer. 2002;2:161–74.

    Article  CAS  PubMed  Google Scholar 

  • Gross J, Lapiere CM. Collagenolytic activity in amphibian tissues: a tissue culture assay. Proc Natl Acad Sci U S A. 1962;48:1014–22.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Gururajan R, Lahti JM, et al. Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2. Genome Res. 1998;8(9):929–39.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Holmbeck K, Bianco P, et al. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell. 1999;99(1):81–92.

    Article  CAS  PubMed  Google Scholar 

  • Hu J, Van den Steen PE, et al. Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases. Nat Rev Drug Discov. 2007;6(6):480–98.

    Article  CAS  PubMed  Google Scholar 

  • Jana S, Paul S, et al. Curcumin as anti-endometriotic agent: implication of MMP-3 and intrinsic apoptotic pathway. Biochem Pharmacol. 2012;83(6):797–804.

    Article  CAS  PubMed  Google Scholar 

  • Jana S, Chatterjee K, et al. Regulation of matrix metalloproteinase-2 activity by COX-2-PGE2-pAKT axis promotes angiogenesis in endometriosis. PLoS One. 2016;11(10):e0163540.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Kessenbrock K, Plaks V, et al. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell. 2010;141(1):52–67.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Khokha R, Murthy A, et al. Metalloproteinases and their natural inhibitors in inflammation and immunity. Nat Rev Immunol. 2013;13(9):649–65.

    Article  PubMed  CAS  Google Scholar 

  • Lopez-Otin C, Matrisian LM. Emerging roles of proteases in tumour suppression. Nat Rev Cancer. 2007;7(10):800–8.

    Article  CAS  PubMed  Google Scholar 

  • Mishra A, Bhattacharya P, et al. An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition. Lung India. 2011;28(3):174–9.

    Article  PubMed  PubMed Central  Google Scholar 

  • Mukherjee A, Swarnakar S. Implication of matrix metalloproteinases in regulating neuronal disorder. Mol Biol Rep. 2015;42(1):1–11.

    Article  CAS  PubMed  Google Scholar 

  • Nagase H, Visse R, et al. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res. 2006;69(3):562–73.

    Article  CAS  PubMed  Google Scholar 

  • Overall CM, Lopez-Otin C. Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat Rev Cancer. 2002;2(9):657–72.

    Article  CAS  PubMed  Google Scholar 

  • Page-McCaw A, Ewald AJ, et al. Matrix metalloproteinases and the regulation of tissue remodelling. Nat Rev Mol Cell Biol. 2007;8(3):221–33.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Sharma AV, Ganguly K, et al. Curcumin heals indomethacin-induced gastric ulceration by stimulation of angiogenesis and restitution of collagen fibers via VEGF and MMP-2 mediated signaling. Antioxid Redox Signal. 2012;16(4):351–62.

    Article  CAS  PubMed  Google Scholar 

  • Swarnakar S, Ganguly K, et al. Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer. J Biol Chem. 2005;280(10):9409–15.

    Article  CAS  PubMed  Google Scholar 

  • Swarnakar S, Paul S, et al. Matrix metalloproteinases in health and disease: regulation by melatonin. J Pineal Res. 2011;50(1):8–20.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, WB, India

    Snehasikta Swarnakar & Sayantan Jana

Authors
  1. Snehasikta Swarnakar
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  2. Sayantan Jana
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Corresponding author

Correspondence to Snehasikta Swarnakar .

Editor information

Editors and Affiliations

  1. Department of Molecular Science and Technology, Ajou University, Suwon, Korea

    Sangdun Choi

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Swarnakar, S., Jana, S. (2018). Matrix Metalloproteinases. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101814

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