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Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 1

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References

  • Anderson DM, Anderson KM, Chang CL, Makarewich CA, Nelson BR, McAnally JR, et al. A micropeptide encoded by a putative long noncoding RNA regulates muscle performance. Cell. 2015;160:595–606.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Arruda AP, Ketzer LA, Nigro M, Galina A, Carvalho DP, de Meis L. Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and sarcoplasmic reticulum Ca2+ ATPase isoform 1 heat production. Endocrinology. 2008;149:6262–71.

    Article  CAS  PubMed  Google Scholar 

  • Brandl CJ, Green NM, Korczak B, MacLennan DH. Two Ca2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences. Cell. 1986;44:597–607.

    Article  PubMed  CAS  Google Scholar 

  • Brandl CJ, deLeon S, Martin DR, MacLennan DH. Adult forms of the Ca2+ATPase of sarcoplasmic reticulum. Expression in developing skeletal muscle. J Biol Chem. 1987;262:3768–74.

    PubMed  CAS  Google Scholar 

  • Burk SE, Lytton J, MacLennan DH, Shull GE. cDNA cloning, functional expression, and mRNA tissue distribution of a third organellar Ca2+ pump. J Biol Chem. 1989;264:18561–8.

    PubMed  CAS  Google Scholar 

  • Chami M, Gozuacik D, Lagorce D, Brini M, Falson P, Peaucellier G, et al. SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis. J Cell Biol. 2001;153:1301–14.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Fajardo VA, Bombardier E, Vigna C, Devji T, Bloemberg D, Gamu D, et al. Co-expression of SERCA isoforms, phospholamban and sarcolipin in human skeletal muscle fibers. PLoS One. 2013;8:e84304.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Kimura T, Nakamori M, Lueck JD, Pouliquin P, Aoike F, Fujimura H, et al. Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1. Hum Mol Genet. 2005;14:2189–200.

    Article  PubMed  CAS  Google Scholar 

  • MacLennan DH. Purification and properties of an adenosine triphosphatase from sarcoplasmic reticulum. J Biol Chem. 1970;245:4508–18.

    PubMed  CAS  Google Scholar 

  • MacLennan DH, Brandl CJ, Korczak B, Green NM. Amino-acid sequence of a Ca2+ + Mg2+-dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence. Nature. 1985;316:696–700.

    Article  PubMed  CAS  Google Scholar 

  • Mázala DA, Pratt SJ, Chen D, Molkentin JD, Lovering RM, Chin ER. SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models. Am J Phys Cell Phys. 2015;308:C699–709.

    Article  CAS  Google Scholar 

  • Michelangeli F, East JM. A diversity of SERCA Ca2+ pump inhibitors. Biochem Soc Trans. 2011;39:789–97.

    Article  PubMed  CAS  Google Scholar 

  • Odermatt A, Taschner PE, Khanna VK, Busch HF, Karpati G, Jablecki CK, et al. Mutations in the gene-encoding SERCA1, the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+ ATPase, are associated with Brody disease. Nat Genet. 1996;14:191–4.

    Article  PubMed  CAS  Google Scholar 

  • Sacchetto R, Bertipaglia I, Giannetti S, Cendron L, Mascarello F, Damiani E, et al. Crystal structure of sarcoplasmic reticulum Ca2+-ATPase (SERCA) from bovine muscle. J Struct Biol. 2012;178:38–44.

    Article  PubMed  CAS  Google Scholar 

  • Sahoo SK, Shaikh SA, Sopariwala DH, Bal NC, Periasamy M. Sarcolipin protein interaction with sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is distinct from phospholamban protein, and only sarcolipin can promote uncoupling of the SERCA pump. J Biol Chem. 2013;288:6881–9.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Toyoshima C. How Ca2+-ATPase pumps ions across the sarcoplasmic reticulum membrane. Biochim Biophys Acta. 2009;1793:941–6.

    Article  PubMed  CAS  Google Scholar 

  • Toyoshima C, Nakasako M, Nomura H, Ogawa H. Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution. Nature. 2000;405:647–55.

    Article  PubMed  CAS  Google Scholar 

  • Winther AM, Bublitz M, Karlsen JL, Møller JV, Hansen JB, Nissen P, Buch-Pedersen MJ. The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm. Nature. 2013;495:265–9.

    Article  PubMed  CAS  Google Scholar 

  • Zádor E, Kósa M. The neonatal sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA1b): a neglected pump in scope. Pflugers Arch. 2015;467:1395–401.

    Article  PubMed  CAS  Google Scholar 

  • Zhao Y, Ogawa H, Yonekura S, Mitsuhashi H, Mitsuhashi S, Nishino I, et al. Functional analysis of SERCA1b, a highly expressed SERCA1 variant in myotonic dystrophy type 1 muscle. Biochim Biophys Acta. 2015;1852:2042–7.

    Article  PubMed  CAS  Google Scholar 

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Acknowledgment

Thank you to C. Toyoshima for allowing to use images and legends of Fig. 1 from his review article (Toyoshima 2009).

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Correspondence to Ernő Zádor .

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Zádor, E., Kósa, M. (2018). Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 1. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101795

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