Synonyms
Ndfip1:
Bypass Sod1p Defects (Bsd2p) (Saccharomyces cerevisiae); Nedd4 family-interacting protein 1 (Ndfip1); Nedd4 family-interacting protein (Ndfip), dNdfip, DmeI, CG32177 (Drosophila Ndfip1); NEDD4 WW domain-binding protein 5 (human); Nedd4 WW domain-binding protein 5 (N4WBP5)
Ndfip2:
KIAA1165; Nedd4 family-interacting protein 2 (Ndfip2); NEDD4 WW domain-binding protein 5A (N4WBP5A)
Historical Background
Nedd4 family-interacting protein 1 (Ndfip1) was first identified in a far-western screen searching for proteins that interact with the WW domains of the Nedd4 ubiquitin ligase (Jolliffe et al. 2000). It was initially named Nedd4 WW domain-binding protein 5 (N4WBP5). Following this discovery, a closely related mammalian protein was identified (named N4WBP5A, now called Ndfip2) and further characterized as belonging to a small group of evolutionarily conserved proteins (Harvey et al. 2002), with a single homologue in yeast [Bsd2p (Hettema et al., 2004)] and Drosophila...
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References
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Foot, N., Kumar, S. (2018). NDFIP1 and NDFIP2. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101705
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DOI: https://doi.org/10.1007/978-3-319-67199-4_101705
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