This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bolton P, Powell J, Rutter M, Buckle V, Yates JR, Ishikawa-Brush Y, Monaco AP. Autism, mental retardation, multiple exostoses and short stature in a female with 46,X,t(X;8)(p22.13;q22.1). Psychiatr Genet. 1995;5:51–5.
Castellone MD, Laukkanen MO, Teramoto H, Bellelli R, Alì G, Fontanini G, Santoro M, Gutkind JS. Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma. Oncogene. 2015 Mar 26;34(13):1679–87.
Dal-Pizzol F, Di Leone LP, Ritter C, Martins MR, Reinke A, Pens Gelain D, Zanotto-Filho A, de Souza LF, Andrades M, Barbeiro DF, Bernard EA, Cammarota M, Bevilaqua LR, Soriano FG, Cláudio J, Moreira F, Roesler R, Schwartsmann G. Gastrin-releasing peptide receptor antagonist effects on an animal model of sepsis. Am J Respir Crit Care Med. 2006;173:84–90.
Furness JB, Kunze WA, Clerc N. The intestine as a sensory organ: neural, endocrine, and immune responses. Am J Phys. 1999;277:922–8.
Ghatei MA, Jung RT, Stevenson JC, Hillyard CJ, Adrian TE, Lee YC, Christofides ND, Sarson DL, Mashiter K, MacIntyre I, Bloom SR. Bombesin: action on gut hormones and calcium in man. J Clin Endocrinol Metab. 1982;54:980–5.
Gupta RA, Dubois RN. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat Rev Cancer. 2001;1:11–21.
Helmich MR, Ives KL, Udupi V, et al. Multiple protein kinase pathways are involved in gastrin-releasing peptide receptor-regulated secretion. J Biol Chem. 1999;274:23901–9.
Jensen RT, Coy DH, Saeed ZA, Heinz-Erian P, Mantey S, Gardner JD. Interaction of bombesin and related peptides with receptors on pancreatic acinar cells. Ann N Y Acad Sci. 1988;547:138–49.
Jensen JA, Carroll RE, Benya RV. The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer. Peptides. 2001;22:689–99.
Kurose H. Gα12 and Gα13 as key regulatory mediator in signal transduction. Life Sci. 2003;74:155–61.
Laukkanen MO, Castellone MD. Gastrin-releasing peptide receptor targeting in cancer treatment: Emerging signaling networks and therapeutic applications. Curr Drug Targets. 2016;17:508–14.
Poitras P, Trudel L, Miller P, Gu CM. Regulation of motilin release: studies with ex vivo perfused canine jejunum. Am J Phys. 1997;272:G4–9.
Rao PN, Klinepeter K, Stewart W, Hayworth R, Grubs R, Pettenati MJ. Molecular cytogenetic analysis of a duplication Xp in a male: further delineation of a possible sex influencing region on the X chromosome. Hum Genet. 1994;94:149–53.
Roesler R, Luft T, Oliveira SH, et al. Molecular mechanisms mediating gastrin-releasing peptide receptor modulation of memory consolidation in the hippocampus. Neuropharmacology. 2006;51:350–7.
Roesler R, Schwartsmann G. Gastrin-releasing peptide receptors in the central nervous system: role in brain function and as a drug target. Front Endocrinol. 2012;3(159).
Severi C, Jensen RT, Erspamer V, D’Arpino L, Coy DH, Torsoli A, Delle Fave G. Different receptors mediate the action of bombesin-related peptides on gastric smooth muscle cells. Am J Phys. 1991;260:G683–90.
Siehler S. Regulation of RhoGEF proteins by G12/13-coupled receptors. Br J Pharmacol. 2009;158:41–9.
Watkins DN, Berman DM, Baylin SB. Hedgehog signaling: progenitor phenotype in small-cell lung cancer. Cell Cycle. 2003;2:196–8.
Weigert N, Li YY, Lippl F, Coy DH, Classen M, Schusdziarra V. Role of endogenous bombesin-peptides during vagal stimulation of gastric acid secretion in the rat. Neuropeptides. 1996;30:521–7.
Zheng R, Iwase A, Shen R, Goodman Jr OB, Sugimoto N, Takuwa Y, Lerner DJ, Nanus DM. Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase. Oncogene. 2006;25:5942–52.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this entry
Cite this entry
Parascandolo, A., Castellone, M.D. (2018). Gastrin-Releasing Peptide Receptor (GRPR). In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101646
Download citation
DOI: https://doi.org/10.1007/978-3-319-67199-4_101646
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-67198-7
Online ISBN: 978-3-319-67199-4
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences