Synonyms
Historical Background
The name “structural mRNA” had been coined in 2005 by Kloc et al. (2005) following discovery that the messenger RNAs (mRNAs) present in frog Xenopus laevis oocytes can have a dual, translational and nontranslational (structural) function (Kloc et al. 2005). These investigators found that maternal VegT mRNA present in the vegetal hemisphere of Xenopus oocytes besides a translational function in the production of VegT protein – a transcription factor regulating endoderm and mesoderm formation in the embryo (Kofron et al. 1999; Zhang et al. 1998) has also an independent, protein-unrelated, function (Heasman et al. 2001; Kloc et al. 2005, 2007, 2011a, b) in the organization and polymerization of cytokeratin filaments in the oocyte (Kloc 2009; Kloc et al. 2005, 2007, 2011a, b). Following this discovery, other structural mRNAs have been described in Drosophila, Xenopus, and HeLa cells (Blower et al. 2005, 2007; Jenny et al. 2006; Kanke et al. 2015;...
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Kloc, M., Kubiak, J.Z. (2018). Structural mRNAs. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101563
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