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C-Reactive Protein

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References

  • Abernethy TJ, Avery OT. The occurrence during acute infections of a protein normally present in the blood: I. Distribution of the reactive protein in patients’ sera and the effect of calcium on the flocculation reaction with C polysaccharide of pneumococcus. J Exp Med. 1941;73:173–82.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Abernethy TJ, Francis T. Studies on the somatic C polysaccharide of pneumococcus: I. cutaneous and serological reactions in pneumonia. J Exp Med. 1937;65:59–73.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Allin KH, Nordestgaard BG. Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer. Crit Rev Clin Lab Sci. 2011;48:155–70.

    Article  PubMed  CAS  Google Scholar 

  • Aref H, Refaat S. CRP evaluation in non-small cell lung cancer. Egypt J Chest Dis Tuberc. 2014;63:717–22.

    Article  Google Scholar 

  • Ash R. Nonspecific precipitins for Pneumococcus fraction C in acute infections. J Infect Dis. 1933;53:89–97.

    Article  CAS  Google Scholar 

  • Laaksonen DE, Niskanen L, Nyyssönen K, Punnonen K, Tuomainen T-P, Valkonen V-P, et al. C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men. Diabetologia. 2004;47:1403–10.

    Article  PubMed  CAS  Google Scholar 

  • Lubell Y, Blacksell SD, Dunachie S, Tanganuchitcharnchai A, Althaus T, Watthanaworawit W, et al. Performance of C-reactive protein and procalcitonin to distinguish viral from bacterial and malarial causes of fever in Southeast Asia. BMC Infect Dis. 2015;15:511.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • MacGregor AJ, Gallimore JR, Spector TD, Pepys MB. Genetic effects on baseline values of C-reactive protein and serum amyloid a protein: a comparison of monozygotic and dizygotic twins. Clin Chem. 2004;50:130–4.

    Article  PubMed  CAS  Google Scholar 

  • Nishikawa H, Shirano M, Kasamatsu Y, Morimura A, Iida K, Kishi T, et al. Comparative usefulness of inflammatory markers to indicate bacterial infection-analyzed according to blood culture results and related clinical factors. Diagn Microbiol Infect Dis. 2016;84:69–73.

    Article  PubMed  CAS  Google Scholar 

  • Obradovic M, Sudar E, Zafirovic S, Stanimirovic J, Labudovic-Borovic M, Isenovic ER. Estradiol in vivo induces changes in cardiomyocytes size in obese rats. Angiology. 2015a;66:25–35.

    Article  PubMed  CAS  Google Scholar 

  • Obradovic MM, Trpkovic A, Bajic V, Soskic S, Jovanovic A, Stanimirovic J, et al. Interrelatedness between C-reactive protein and oxidized low-density lipoprotein. Clin Chem Lab Med. 2015b;53:29–34.

    Article  PubMed  CAS  Google Scholar 

  • Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest. 2003;111:1805–12.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA. 2001;286:327–34.

    Article  PubMed  CAS  Google Scholar 

  • Ridker PM. C-reactive protein: eighty years from discovery to emergence as a major risk marker for cardiovascular disease. Clin Chem. 2009;55:209–15.

    Article  PubMed  CAS  Google Scholar 

  • Tillett WS, Francis T. Serological reactions in pneumonia with a non-protein somatic fraction of pneumococcus. J Exp Med. 1930;52:561–71.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Trpkovic A, Stanimirovic J, Resanovic I, Otasevic P, Jevremovic D, Djordje R, et al. High sensitivity C-reactive protein and cardiovascular risk prediction. Curr Pharm Anal. 2015;11:60–5.

    Article  CAS  Google Scholar 

  • Westhuyzen J, Healy H. Review: biology and relevance of C-reactive protein in cardiovascular and renal disease. Ann Clin Lab Sci. 2000;30:133–43.

    PubMed  CAS  Google Scholar 

  • Xi S, Dyer KF, Kimak M, Zhang Q, Gooding WE, Chaillet JR, et al. Decreased STAT1 expression by promoter methylation in squamous cell carcinogenesis. J Natl Cancer Inst. 2006;98:181–9.

    Article  PubMed  CAS  Google Scholar 

  • Yue CC, Muller-Greven J, Dailey P, Lozanski G, Anderson V, Macintyre S. Identification of a C-reactive protein binding site in two hepatic carboxylesterases capable of retaining C-reactive protein within the endoplasmic reticulum. J Biol Chem. 1996;271:22245–50.

    Article  PubMed  CAS  Google Scholar 

  • Zimmermann O, Li K, Zaczkiewicz M, Graf M, Liu Z, Torzewski J, et al. C-Reactive protein in human atherogenesis: facts and fiction, C-reactive protein in human atherogenesis: facts and fiction. Mediat Inflamm Mediat Inflamm. 2014;1:2014–561428.

    Google Scholar 

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Acknowledgments

This work is supported by grants No.173033 (to E.R.I) from the Ministry of Science, Republic of Serbia.

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Authors and Affiliations

  1. Laboratory for Radiobiology and Molecular Genetics, Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia

    Andreja Trpkovic, Milan Obradovic, Nina Petrovic, Radoslav Davidovic, Emina Sudar-Milovanovic & Esma R. Isenovic

Authors
  1. Andreja Trpkovic
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  2. Milan Obradovic
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  3. Nina Petrovic
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  4. Radoslav Davidovic
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  5. Emina Sudar-Milovanovic
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  6. Esma R. Isenovic
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Corresponding author

Correspondence to Esma R. Isenovic .

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Editors and Affiliations

  1. Department of Molecular Science and Technology, Ajou University, Suwon, Korea

    Sangdun Choi

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Trpkovic, A., Obradovic, M., Petrovic, N., Davidovic, R., Sudar-Milovanovic, E., Isenovic, E.R. (2018). C-Reactive Protein. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, Cham. https://doi.org/10.1007/978-3-319-67199-4_101542

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