Reference work entry
B-MYB is a member of the Myeloblastosis transcription factor (TF) family which is present in all vertebrates. The other members of the family are A-MYB and c-MYB. c-MYB was the first one to be discovered as a homologue of the v-MYB oncogene carried by two different avian leukemia viruses, Avian Myeloblastosis Virus (AMV) and E26 (Fig. 1) which cause acute myeloblastic leukemia and can also transform immature hematopoietic cells in culture.
- Johung K, Goodwin EC, DiMaio D. Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence. J Virol. 2007;81(5):2102–16. https://doi.org/10.1128/JVI.02348-06.CrossRefPubMedCentralPubMedGoogle Scholar
- Li J, Bai X, Cui S, Fu B, Chen X. Effect of rapamycin on high glucose-induced autophagy impairment, oxidative stress and premature senescence in rat mesangial cells in vitro. Nan Fang Yi Ke Da Xue Xue Bao = J Southern Med University. 2012;32(4):467–71. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/22543123.
- Litovchick L, Sadasivam S, Florens L, Zhu X, Swanson SK, Velmurugan S, et al. Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. Mol Cell. 2007;26(4):539–51. https://doi.org/10.1016/j.molcel.2007.04.015.CrossRefPubMedCentralPubMedGoogle Scholar
- Robinson C, Light Y, Groves R, Mann D, Marias R, Watson R. Cell-cycle regulation of B-Myb protein expression: specific phosphorylation during the S phase of the cell cycle. Oncogene. 1996;12(9):1855–64. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/8649845.
- Saville MK & Watson RJ. (1998). The cell-cycle regulated transcription factor B-Myb is phosphorylated by Cyclin A/Cdk2 at sites that enhance its transactivation properties. Oncogene. 1998;17(21):2679–89. https://doi.org/https://dx.doi.org/10.1038/sj.onc.1202503.PubMedPubMedCentralCrossRefGoogle Scholar
- Schmit F, Korenjak M, Mannefeld M, Schmitt K, Franke C, von Eyss B, et al. LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes. Cell Cycle. 2007;6(15):1903–13. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17671431.PubMedPubMedCentralCrossRefGoogle Scholar
- Zhan M, Riordon DR, Yan B, Tarasova YS, Bruweleit S, Tarasov KV, et al. The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells. PLoS One. 2012; https://doi.org/10.1371/journal.pone.0042350.CrossRefPubMedPubMedCentralGoogle Scholar
© Springer International Publishing AG 2018