p38 Gamma MAPK
The work in Chen lab was supported by grants from National Institutes of Health, Department of Veterans Affair (VA), and Department of Defense (DoD). We would like to acknowledge the former lab members Drs. Jung Tang, Rocky Pramanik, Song-Wang Hou, Mathew Loesch, Adrienne Lepp, Padmanaban S. Suresh, Shao Ma, and Ning Yin for their contributions.
- Ho RC, Alcazar O, Fujii N, Hirshman MF, Goodyear LJ. p38γ MAPK regulation of glucose transporter expression and glucose uptake in Ly myotubes and mouse skeletal muscle. Am J Phys Regul Integr Comp Phys. 2003;286:R342–R9.Google Scholar
- Marinissen MJ, Chiariello M, Pallante M, Gutkind JS. A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5. Mol Cell Biol. 1999;19:4289–301.PubMedPubMedCentralCrossRefGoogle Scholar
- Ozes O, Blatt LM, Seiwert SD. Use of pirfenidone in therapeutic regimens. United States Patent-US 7,407,973 B2. 2008;Aug. 5th:1–46.Google Scholar
- Qi X, Zhi H, Lepp A, Wang P, Huang J, Basir Z, et al. p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription. J Biol Chem. 2012;287:14681–91.PubMedPubMedCentralCrossRefGoogle Scholar
- Risco A, Fresno C, Mambol A, Alsina-Beauchamp D, MacKenzie KF, Yang HA. p38γ and p38δ kinases regulate the toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation. Proc Natl Acad Sci U S A. 2012;109:11200–5.PubMedPubMedCentralCrossRefGoogle Scholar