Synonyms
Celomic cyst; Pericardial cyst
Definition
A rare, unilocular congenital cyst occurring in mediastinum with close connection to the pericardium (pericardial cyst) or without connection to pericardium (mesothelial cyst). It is lined by mesothelial cells in a one layer. Mesothelial cyst may be associated with chest pain, dysphagia, or dyspnea.
Clinical Features
Incidence
Rare.
Age
All ages, more common in adults.
Sex
Both sexes are equally affected.
Site
Mesothelial cyst can occur throughout mediastinum, if pericardial than they are located in the middle mediastinum.
Treatment
Surgery (for symptomatic cysts) and percuataneous needle aspiration.
Outcome
Good.
Macroscopy
Thin-walled unilocular cyst with smooth inner and outer surface filled with clear serous content.
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References and Further Reading
Plaza, J. A., Moran, C. A., & Suster, S. (2010). Thymus and mediastinum. In P. Gattuso, V. B. Reddy, O. David, D. J. Spitz, & M. H. Haber (Eds.), Differential diagnosis in surgical pathology (p. 284). Philadelphia: Saunders Elsevier.
Shimosato, Y., Mukai, K., & Matsuno, Y. (2010). Bronchogenic cyst. In S. G. Silverberg (Ed.), AFIP Atlas of tumor pathology. Tumors of the mediastinum (p. 307). Washington, DC: American Registry of Pathology.
Wick, M. R. (2005). Cystic lesions of the mediastinum. Seminars in Diagnostic Pathology, 22, 241–253.
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Brcic, I. (2018). Mesothelial Cyst, Mediastinal. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_41
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DOI: https://doi.org/10.1007/978-3-319-66796-6_41
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