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Mesothelial Cyst, Mediastinal

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Pathology of the Pleura and Mediastinum

Part of the book series: Encyclopedia of Pathology ((EP))

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Synonyms

Celomic cyst; Pericardial cyst

Definition

A rare, unilocular congenital cyst occurring in mediastinum with close connection to the pericardium (pericardial cyst) or without connection to pericardium (mesothelial cyst). It is lined by mesothelial cells in a one layer. Mesothelial cyst may be associated with chest pain, dysphagia, or dyspnea.

Clinical Features

  • Incidence

    Rare.

  • Age

    All ages, more common in adults.

  • Sex

    Both sexes are equally affected.

  • Site

    Mesothelial cyst can occur throughout mediastinum, if pericardial than they are located in the middle mediastinum.

  • Treatment

    Surgery (for symptomatic cysts) and percuataneous needle aspiration.

  • Outcome

    Good.

Macroscopy

Thin-walled unilocular cyst with smooth inner and outer surface filled with clear serous content.

Microscopy

A cyst is lined by one layer of mesothelial cells, which can be flat or cuboidal, and are surrounded by loose connective tissue (Figs. 1 and 2). The wall of the cyst is fibrous, without cartilage, smooth...

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References and Further Reading

  • Plaza, J. A., Moran, C. A., & Suster, S. (2010). Thymus and mediastinum. In P. Gattuso, V. B. Reddy, O. David, D. J. Spitz, & M. H. Haber (Eds.), Differential diagnosis in surgical pathology (p. 284). Philadelphia: Saunders Elsevier.

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  • Shimosato, Y., Mukai, K., & Matsuno, Y. (2010). Bronchogenic cyst. In S. G. Silverberg (Ed.), AFIP Atlas of tumor pathology. Tumors of the mediastinum (p. 307). Washington, DC: American Registry of Pathology.

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  • Wick, M. R. (2005). Cystic lesions of the mediastinum. Seminars in Diagnostic Pathology, 22, 241–253.

    Article  PubMed  Google Scholar 

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Correspondence to Iva Brcic .

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Brcic, I. (2018). Mesothelial Cyst, Mediastinal. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_41

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  • DOI: https://doi.org/10.1007/978-3-319-66796-6_41

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-66795-9

  • Online ISBN: 978-3-319-66796-6

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