Skip to main content
SpringerLink
Log in
Book cover

Pathology of the Pleura and Mediastinum pp 341–343Cite as

Primary Squamous Cell Carcinoma, Pleural

  • Reference work entry
  • First Online:

  • 49 Accesses

Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

No synonyms have been described for this entity.

Definition

Carcinoma arising from squamous epithelial cells, morphologically characterized by proliferation of atypical, often pleomorphic squamous cells, and graded as well, moderately, or poorly differentiated and well-differentiated carcinomas are usually associated with keratin production and presence of intercellular bridges between adjacent cells; subtypes include basaloid, clear cell type, papillary, and small cell nonkeratinizing.

Clinical Features

  • Incidence

    Primary pleural squamous cell carcinoma (SCC) is a very rare pleural malignancy which has seldom been reported. Cases of squamous cell carcinoma arising from the pleura in patients with a chronically draining empyema cavity have rarely been reported. Chronic pleural inflammation may therefore be one of the causes of primary pleural SCC.

  • Age

    Malignant pleural tumors are usually seen in older adults.

  • Sex

    Primary SCC is mostly reported in males.

  • Site...

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   599.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   899.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References and Further Reading

  • Cardillo, G., Facciolo, F., Cavazzana, A. O., Capece, G., Gasparri, R., & Martelli, M. (2000). Localized (solitary) fibrous tumors of the pleura: An analysis of 55 patients. The Annals of Thoracic Surgery, 70(6), 1808–1812.

    Article  CAS  PubMed  Google Scholar 

  • Franke, M., Chung, H. D., & Johnson, F. E. (2010). Squamous cell carcinoma arising from the pleura after pneumonectomy for squamous cell carcinoma of the lung. American Journal of Surgery, 199(4), e34–e35.

    Article  PubMed  Google Scholar 

  • Lin, X. M., Chi, C., Chen, J., Liu, Y., Li, P., & Yang, Y. (2013). Primary pleural squamous cell carcinoma misdiagnosed as localized mesothelioma: A case report and review of the literature. Journal of Cardiothoracic Surgery, 8, 50.

    Article  PubMed  PubMed Central  Google Scholar 

  • Magdeleinat, P., Alifano, M., Petino, A., Le Rochais, J. P., Dulmet, E., Galateau, F., et al. (2002). Solitary fibrous tumors of the pleura: Clinical characteristics, surgical treatment and outcome. European Journal of Cardio-Thoracic Surgery: Official Journal of the European Association for Cardio-Thoracic Surgery, 21(6), 1087–1093.

    Article  Google Scholar 

  • Ordonez, N. G. (2005). Mesothelioma with clear cell features: An ultrastructural and immunohistochemical study of 20 cases. Human Pathology, 36(5), 465–473.

    Article  PubMed  Google Scholar 

  • Ordonez, N. G. (2007). What are the current best immunohistochemical markers for the diagnosis of epithelioid mesothelioma? A review and update. Human Pathology, 38(1), 1–16.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University of Texas Medical Branch at Galveston, Galveston, TX, USA

    Sara Faiz

  2. Department of Pathology, The University of Mississippi Medical School, The University of Mississippi Medical Center, Jackson, MS, USA

    Timothy Craig Allen

Authors
  1. Sara Faiz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Timothy Craig Allen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sara Faiz .

Editor information

Editors and Affiliations

  1. Department of Pathology, The University of Mississippi Medical School, The University of Mississippi Medical Center, Jackson, MS, USA

    Timothy Craig Allen

  2. Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA

    Saul Suster

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Faiz, S., Allen, T.C. (2018). Primary Squamous Cell Carcinoma, Pleural. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_383

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-66796-6_383

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-66795-9

  • Online ISBN: 978-3-319-66796-6

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation