Pathology of the Pleura and Mediastinum

2018 Edition
| Editors: Timothy Craig Allen, Saul Suster

Postcardiac Injury Syndrome

  • Christopher P. MarquezEmail author
Reference work entry


Dressler syndrome; Postcardiotomy syndrome; Postcommissurotomy syndrome; Post-myocardial infarction syndrome; Postpericardiotomy syndrome; Post-traumatic pericarditis


Postcardiac injury syndrome (PCIS) is a term used to describe late pericarditis or pleuropericarditis following a myocardial, pericardial, and/or pleural insult. Other terms describe the same condition based on the inciting event, such as Dressler syndrome or post-myocardial infarction syndrome with an acute myocardial infarction and postpericardiotomy syndrome with cardiac surgery.

PCIS frequently presents with chest discomfort, pericardial effusion, elevated inflammatory markers (i.e., CRP & ESR), pleural effusion, dyspnea, low-grade fever, and/or a pleural or pericardial friction rub. These features generally occur no later than 3 months after the inciting event with most patients being affected within the first month, especially 1 week. It may last from a few days to a few weeks, with complete...

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References and Further Reading

  1. Hoit, B. D. Post-cardiac injury syndromes. Accessed 10 Jan 2014.
  2. Imazio, M., & Hoit, B. D. (2013). Post-cardiac injury syndromes. An emerging cause of pericardial diseases. International Journal of Cardiology, 168, 648–652.CrossRefPubMedGoogle Scholar
  3. Imazio, M., Brucato, A., Rovere, M. E., Gandino, A., Cemin, R., Ferrua, S., Maestroni, S., Barosi, A., Simon, C., Ferrazzi, P., Belli, R., Trinchero, R., Spodick, D., & Adler, Y. (2011). Contemporary features, risk factors, and prognosis of the post-pericardiotomy syndrome. The American Journal of Cardiology, 108, 1183–1197.CrossRefPubMedGoogle Scholar
  4. Khan, A. H. (1992). The postcardiac injury syndromes. Clinical Cardiology, 15, 67–72.CrossRefPubMedGoogle Scholar
  5. Silver, M., et al. (2001). Cardiovascular pathology (3rd ed.). Philadelphia: Churchill Livingstone. Print.Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PathologyUniversity of Texas Medical BranchGalvestonUSA