Pathology of the Pleura and Mediastinum

2018 Edition
| Editors: Timothy Craig Allen, Saul Suster

Fibrous and Fibrinous Pleuritis

  • Koichi HonmaEmail author
Reference work entry


Chronic pleuritis; Fibrinous and fibrous pleurisy; Fibrosing pleuritis; Fibrosis of the pleura; Fibrothorax


Fibrinous pleuritis refers to a fibrinous inflammation of the pleura frequently accompanied by serous and sometimes sanguineous effusion in the pleural cavity and ending up with fibrosis of the pleura through organization of the inflammatory exudates. A wide range of etiologic factors or underlying conditions concerns this type of inflammation, which includes collagen vascular disease, exposure to mineral dust (asbestos and silicates), drugs and other iatrogenic conditions, uremia, pneumothorax, and secondary to pulmonary infection and infarction.

Organization of the fibrinous exudate occurs with infiltration of the inflammatory cells (lymphocytes, macrophages) and ingrowth of fibroblasts and blood vessels and eventually gives rise to collagenization of the pleura (fibrous pleuritis), which frequently causes fibrous adhesion of both parietal and visceral...

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References and Further Reading

  1. Corrin, B., & Addis, B. J. (1990). Histopathology of the pleura. Respiration, 57, 160–175.CrossRefPubMedGoogle Scholar
  2. English, J. C., & Leslie, K. O. (2006). Pathology of the pleura. Clinics in Chest Medicine, 27, 157–180.CrossRefPubMedGoogle Scholar
  3. Jantz, M. A., & Anthony, V. B. (2006). Pleural fibrosis. Clinics in Chest Medicine, 27, 181–191.CrossRefPubMedGoogle Scholar
  4. Müller, K. M. (1983). Pleura. In W. Doerr & G. Seifert (Eds.), Pathologie der lunge (pp. 1295–1398). Berlin/Heidelberg/New York/Tokyo: Springer.Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PathologyDokkyo University School of MedicineMibuJapan