Pathology of the Pleura and Mediastinum

2018 Edition
| Editors: Timothy Craig Allen, Saul Suster

Desmoid Tumor, Pleural

  • Melissa Van DellenEmail author
Reference work entry


Aggressive fibromatosis; Deep fibromatosis; Desmoid fibroma; Desmoid-type fibromatosis; Desmoma; Desmoplastic fibroma; Extra-abdominal desmoid tumor; Extra-abdominal fibromatosis; Intrathoracic desmoid tumor; Musculoaponeurotic fibromatosis


Desmoid tumor is a soft tissue neoplasm which falls under the more broad classification of fibromatosis. It arises principally in soft tissue and rarely in the pleura.

Although typically benign, desmoid tumor can be locally aggressive with a tendency to recur and is therefore considered a primary pleural neoplasm of intermediate malignant potential. Desmoid tumor is not known to metastasize; however, infiltration into adjacent organs and blood vessels may result in morbidity and mortality.

Clinical Features

  • Incidence

    The incidence of desmoid tumors in the general population is 2–4 cases per million per year. However, intrathoracic desmoid tumors, such as those arising in the pleura, are even more rare and account for...

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References and Further Reading

  1. Bölke, E., H Krasniqi, H., Lammering, G., Engers, R., Matuschek, C., Gripp, S., Gerber, P. A., Fischer, G., Peiper, M., Shaikh, S., Budach, W., & Orth, K. (2009). Chest wall and intrathoracic desmoid tumors: surgical experience and review of the literature. European Journal of Medical Research, 14, 240–243.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Brodsky, J. T., Gordon, M. S., Hajdu, S. I., & Burt, M. (1992). Desmoid tumors of the chest wall: A locally recurrent problem. Journal of Thoracic and Cardiovascular Surgery, 104, 900–903.PubMedGoogle Scholar
  3. Granville, L., Laga, A. C., Allen, T. C., Dishop, M., Roggli, V. L., Churg, A., Zander, D. S., & Cagle, P. T. (2005). Review and update of uncommon primary pleural tumors: A practical approach to diagnosis. Archives of Pathology & Laboratory Medicine, 129(11), 1428–1443.Google Scholar
  4. Posner, M. C., Shiu, M. H., Newsome, J. L., Hajdu, S. I., Gaynor, J. J., & Brennan, M. F. (1989). The desmoid tumor. Not a benign disease. Archives of Surgery, 124(2), 191–196.CrossRefPubMedGoogle Scholar
  5. Shields, C. J., Winter, D. C., Kirwan, W. O., & Redmond, H. P. (2001). Desmoid tumours. European Journal of Surgical Oncology, 27, 701–706.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PathologyUniversity of Texas Medical BranchGalvestonUSA