Synonyms
CFP; CFPT; CFT; CTP
Definition
Calcifying fibrous pseudotumor (CFP) is an extremely rare benign fibrous lesion that was originally described by Rosenthal and Abdul-Karim as “childhood fibrous tumor with psammoma bodies” in 1988, and the term itself was introduced by Fetsch and associates with an analysis of 10 cases in 1993. In the new classification system by the World Health Organization in 1999, CFP was classified as a soft tissue tumor. CFP has its unique histopathologic features characterized by a dense hyalinized collagenous tissue interspersed with benign spindle cells, chronic inflammatory cells infiltrate, and psammomatous and/or dystrophic calcifications. CFP most commonly arises in the extremities, followed by the trunk, inguinal and scrotal regions, and the head and neck. Rare cases have been reported in the mediastinum, pleura, and visceral peritoneum. In the newly published Classification of Tumors of the Lung, Pleura, Thymus, and Heartby the World Health...
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences and Further Reading
Fetsch, J. F., Montgomery, E. A., & Meis, J. M. (1993). Calcifying fibrous pseudotumor. American Journal of Surgical Pathology, 17, 502–508.
Hill, K. A., Gonzalez-Crussi, F., & Chou, P. M. (2001). Calcifying fibrous pseudotumor versus inflammatory myofibroblastic tumor: A histological and immunohistochemical comparison. Modern Pathology, 14, 784–790.
Rosenthal, N. S., & Abdul-Karim, F. W. (1988). Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Archives of Pathology and Laboratory Medicine, 112, 798–800.
Suh, J. H., Shin, O. R., & Kim, Y. H. (2008). Multiple calcifying fibrous pseudotumor of the pleura. Journal of Thoracic Oncology, 3, 1356–1358.
Van Dorpe, J., Ectors, N., Geboes, K., D’Hoore, A., & Scoit, R. (1999). Is calcifying fibrous pseudotumor a late sclerosing stage of inflammatory myofibroblastic tumor? American Journal of Surgical Pathology, 23, 329–335.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this entry
Cite this entry
He, J. (2018). Calcifying Fibrous Pseudotumor. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_348
Download citation
DOI: https://doi.org/10.1007/978-3-319-66796-6_348
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-66795-9
Online ISBN: 978-3-319-66796-6
eBook Packages: MedicineReference Module Medicine