Definition
Unilocular or multilocular epithelial lined cavity with thymic tissue in the wall of the cyst. They are benign and found in the neck and mediastinum, following embryologic movement of the thymus from the mandibular angle to the manubrium of the sternum.
Clinical Features
Incidence
Congenital thymic cysts are very rare.
Age
Congenital thymic cyst can occur at any age. When present in children, they occur as masses in the neck, while in adults, they are mostly asymptomatic, unless there is compression of some organs or structures nearby.
Sex
There is no predilection for either sex.
Site
Congenital thymic cysts occur in the neck and mediastinum, usually anterosuperior.
Treatment
Surgical excision if symptomatic.
Outcome
Since congenital thymic cysts are benign lesions, surgery is curative, unless malignant neoplasm is present when additional treatment is needed.
Macroscopy
Congenital thymic cysts are usually unilocular but can be also multilocular. If in the neck region they...
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Leong, A. S., & Brown, J. H. (1984). Malignant transformation in a thymic cyst. American Journal of Surgical Pathology, 8, 471–475.
Scharifker, D. (2006). True thymic hyperplasia associated with a unilocular thymic cyst: An unusual combination not previously reported. Annals of Diagnostic Pathology, 10, 32–35.
Shimosato, Y., Mukai, K., & Matsuno, Y. (2010). Thymic cyst. In S. G. Silverberg (Ed.), AFIP Atlas of tumor pathology. Tumors of the mediastinum (pp. 262–263). Washington, DC: American Registry of Pathology.
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Brcic, L. (2018). Congenital Thymic Cyst. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_13
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DOI: https://doi.org/10.1007/978-3-319-66796-6_13
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