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Neurological Manifestations of Endocrine Disorders

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Endocrinology and Systemic Diseases

Part of the book series: Endocrinology ((ENDOCR))

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Abstract

Endocrine disorders may sometimes present with neurological symptoms due to involvement of either the central or peripheral nervous systems. Neurological manifestations of endocrine disorders are highly variable, may be serious, and occasionally cause a medical emergency. The initial symptoms of an endocrine disorder can be exclusively neurological, and, therefore, prompt referral to a neurologist can ensure an early diagnosis. As most endocrine disorders are treatable, their associated neurological manifestations are potentially reversible. An awareness of the neurological manifestations associated with endocrine disorders can facilitate early diagnosis and the implementation of specific treatment, often enabling resolution of the neurological complications without permanent sequelae. This review focuses on the neurological manifestations of endocrine disorders including obesity, diabetes mellitus, and disorders of pituitary gland, thyroid gland, parathyroid gland, adrenal glands, and gonads.

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Abbreviations

ACTH:

Adrenocorticotropic hormone

ADH:

Antidiuretic hormone

CK:

Creatine kinase

CSF:

Cerebrospinal fluid

CT:

Computed tomography

EEG:

Electroencephalography

EMG:

Electromyography

FSH:

Follicle-stimulating hormone

GH:

Growth hormone

GnRH:

Gonadotropin-releasing hormone

IGF-1A:

Insulin-like growth factor 1

LH:

Luteinizing hormone

MEN:

Multiple endocrine neoplasia

MRI:

Magnetic resonance imaging

PET:

Positron emission tomography

PRL:

Prolactin

PTH:

Parathyroid hormone

SIADH:

Syndrome of inappropriate antidiuretic hormone secretion

TRH:

Thyrotropin-releasing hormone

TSH:

Thyroid-stimulating hormone

VLCFAs:

Long chain fatty acids

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Authors and Affiliations

  1. Departamento de Neurología, Clínica Universidad de Navarra, Pamplona, Spain

    Pablo Irimia Sieira, Ane Mínguez Olaondo & Eduardo Martínez-Vila

  2. Neurology Department, Beaumont Hospital, Dublin 9, Ireland

    Martin Ruttledge

Authors
  1. Pablo Irimia Sieira
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  2. Ane Mínguez Olaondo
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  3. Eduardo Martínez-Vila
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  4. Martin Ruttledge
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Corresponding author

Correspondence to Pablo Irimia Sieira .

Editor information

Editors and Affiliations

  1. Dept of Biomed Sci & Human Oncology, Aldo Moro University Medical Sch Dept of Biomed Sci & Human Oncology, Bari, Italy

    Piero Portincasa

  2. Department of Endocrinology, Clinica Universidad de Navarra Department of Endocrinology, Pamplona, Spain

    Gema Frühbeck

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Irimia Sieira, P., Mínguez Olaondo, A., Martínez-Vila, E., Ruttledge, M. (2019). Neurological Manifestations of Endocrine Disorders. In: Portincasa, P., Frühbeck, G. (eds) Endocrinology and Systemic Diseases. Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-319-66362-3_11-1

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  • DOI: https://doi.org/10.1007/978-3-319-66362-3_11-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-66362-3

  • Online ISBN: 978-3-319-66362-3

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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