Skip to main content

Syringomatous Tumor of the Nipple

  • Reference work entry
  • First Online:
Breast Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 1181 Accesses

Synonyms

Infiltrating syringomatous adenoma of the nipple; Syringomatous adenoma of the nipple

Definition

Syringomatous tumor of the nipple/areola region (SAN) is a benign rare condition, which is typically observed in the dermal/subcutaneous region of the nipple area and which exhibits sweat gland differentiation (Ishikawa et al. 2015; Montgomery et al. 2014; Boecker et al. 2014). These tumors have no metastastic potential but can recur if removed incompletely (Ishikawa et al. 2015; Montgomery et al. 2014; Boecker et al. 2014).

Clinical Features

  • Incidence

    This type of nipple tumor is very rare, accounting less than 1% of all tumors arising in the breast. Until now, 39 cases were reported in the English literature, mostly in form of case reports. Thirty seven patients were female, and two were males (Ishikawa et al. 2015; Montgomery et al. 2014; Oo and Xiao 2009; Page et al. 2009; Jones et al. 1989; Carter and Dyess 2004; Rosen 1983). The original description of nipple syringomatous...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 439.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 649.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References and Further Reading

  • Boecker, W., Stenman, G., Loening, T., Andersson, M. K., Sinn, H. P., Barth, P., Oberhellmann, F., Bos, I., Berg, T., Marusic, Z., Samoilova, V., & Buchwalow, I. (2014). Differentiation and histogenesis of syringomatous tumour of the nipple and low-grade adenosquamous carcinoma: Evidence for a common origin. Histopathology, 65, 9–23.

    Article  PubMed  Google Scholar 

  • Carter, E., & Dyess, D. L. (2004). Infiltrating syringomatous adenoma of the nipple: A case report and 20-year retrospective review. The Breast Journal, 10, 443–447.

    Article  PubMed  Google Scholar 

  • Ishikawa, S., Sako, H., Masuda, K., Tanaka, T., Akioka, K., Yamamoto, Y., Hosokawa, Y., & Manabe, T. (2015). Syringomatous adenoma of the nipple: A case report. Journal of Medical Case Reports, 13, 256.

    Article  Google Scholar 

  • Jones, M. W., Norris, H. J., & Snyder, R. C. (1989). Infiltrating syringomatous adenoma of the nipple. A clinical and pathological study of 11 cases. The American Journal of Surgical Pathology, 13, 197–201.

    Article  CAS  PubMed  Google Scholar 

  • Montgomery, N. D., Bianchi, G. D., Klauber-Demore, N., & Budwit, D. A. (2014). Bilateral syringomatous adenomas of the nipple: Case report with immunohistochemical characterization of a rare tumor mimicking malignancy. American Journal of Clinical Pathology, 141, 727–731.

    Article  PubMed  Google Scholar 

  • Oo, K. Z., & Xiao, P. Q. (2009). Infiltrating syringomatous adenoma of the nipple: Clinical presentation and literature review. Archives of Pathology & Laboratory Medicine, 133, 1487–1489.

    Google Scholar 

  • Page, R. N., Dittrich, L., King, R., Boulos, F., & Page, D. L. (2009). Syringomatous adenoma of the nipple occurring within a supernumerary breast: A case report. Journal of Cutaneous Pathology, 36, 1206–1209.

    Article  PubMed  Google Scholar 

  • Rosen, P. P. (1983). Syringomatous adenoma of the nipple. The American Journal of Surgical Pathology, 7, 739–745.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zsuzsanna Varga .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Varga, Z., Moskovszky, L. (2020). Syringomatous Tumor of the Nipple. In: Sapino, A., Kulka, J. (eds) Breast Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-62539-3_4733

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-62539-3_4733

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-62538-6

  • Online ISBN: 978-3-319-62539-3

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics