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Desvenlafaxine

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Generic Name

Desvenlafaxine

Brand Name

Pristiq, Khedzla

Class

Antidepressants, serotonin norepinephrine reuptake inhibitors.

Proposed Mechanism(s) of Action

Increases serotonin and norepinephrine by blocking both serotonin and norepinephrine reuptake pumps.

Indication

Major depressive disorder.

Off-Label Use

Neuropathic pain, chronic pain, generalized anxiety disorder, stress urinary incontinence, and fibromyalgia.

Side Effects

Serious

Seizures, hypomania, and suicidal ideation.

Common

Nausea, headache, diarrhea, dry mouth, constipation, fatigue.

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References and Readings

  • Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.

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  • Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.

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Correspondence to Efrain Antonio Gonzalez .

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© 2018 Springer International Publishing AG, part of Springer Nature

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Gonzalez, E.A. (2018). Desvenlafaxine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_9274

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