Synonyms
Diffusion kurtosis imaging; Diffusion kurtosis mapping; Diffusion tensor imaging; Diffusion weighted imaging; DKI; DKM; DTI; DWI; Fibre bundle orientation; Gaussian; Ischemia; Water diffusion; White matter hyperintensities; White matter tracts; WMH
Definition
In biological tissues, the presence of barriers (e.g., cell membranes) alters the water diffusion so that the actual diffusion diverges from the theoretical Gaussian distribution expected in a homogeneous system (i.e., a glass of water). Diffusional kurtosis imaging (DKI) is a diffusion-weighted MRI method which measures both Gaussian and non-Gaussian properties of water diffusion (Jensen et al. 2005). As such, it allows the characterization of diffuse microscopic injury in both anisotropic and isotropic systems (i.e., white matter tracts and grey matter) (Raz et al. 2013; Fieremans et al. 2011). In comparison with other diffusion imaging techniques, DKI shows a higher accuracy in the estimation of fiber bundle...
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Inglese, M., Petracca, M. (2018). Diffusion Kurtosis Mapping. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_9079
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DOI: https://doi.org/10.1007/978-3-319-57111-9_9079
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