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Mediodorsal Nucleus of Thalamus

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  • First Online:
Encyclopedia of Clinical Neuropsychology

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Synonyms

Dorsomedial nucleus of the thalamus

Definition

The mediodorsal nucleus of the thalamus (MD) is the principal relay to the prefrontal cortex involved in personality.

Current Knowledge

The mediodorsal nucleus of the thalamus (MD) is situated dorsomedially to the internal medullary lamina and is the principal relay to the prefrontal cortex involved in personality. The MD is divided into three subdivisions: magnocellular, parvocellular, and densocellular (or multiform) subnuclei based on anatomical location and cytoarchitecture; however, the subdivision nomenclature varies throughout the literature (Kandel and Schwartz 2000; Boller et al. 2003). The magnocellular subnucleus mainly receives inputs from the amygdala, olfactory tubercle, and entorhinal cortex and sends projections to the orbital and ventromedial frontal lobe involved in acknowledging emotional significance for sights and smells. The parvocellular and densocellular subnuclei receive inputs from the superior...

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References and Readings

  • Boller, F., Grafman, J., Robertson, I. H., Berndt, R. S., & Rizzolatti, G. (2003). Handbook of neuropsychology. Amsterdam: Elsevier.

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  • Conn, P. M. (Ed.). (2003). Neuroscience in medicine. Totawa: Humana Press.

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  • Galila Agam, I. P. E., & Belmaker, R. H. (Eds.). (2001). The postmortem brain in psychiatric research. New York: Kluwer.

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  • Kandel, E. R., & Schwartz, J. H. (2000). Principles of neural science. New York: McGraw-Hill.

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Author information

Authors and Affiliations

  1. Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA, USA

    Audrey Lafrenaye

Authors
  1. Audrey Lafrenaye
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Corresponding author

Correspondence to Audrey Lafrenaye .

Editor information

Editors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, VA, USA

    Jeffrey S. Kreutzer

  2. Kessler Foundation, Pleasant Valley Way, West Orange, NJ, USA

    John DeLuca

  3. Independent Practice, Wynnewood, PA, USA

    Bruce Caplan

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Lafrenaye, A. (2018). Mediodorsal Nucleus of Thalamus. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_331

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