Synonyms
Cytotoxic edema; Vasogenic edema
Definition
Cerebral edema is an increase in the water content of the brain that leads to brain swelling. It may be divided into two broad categories: vasogenic and cytotoxic.
Vasogenic edema involves a disruption in the blood-brain barrier with leakage of fluid from the intravascular space.
In cytotoxic edema, the blood-brain barrier is intact, and there is an increase in the intracellular fluid compartment.
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Beaumont, A., Marmarou, A., & Ward, J. D. (2001). Intracranial hypertension mechanisms and management. In D. G. McClone (Ed.), Pediatric neurosurgery (pp. 619–633). Philadelphia: W. B. Saunders.
Greenberg, M. S. (1997). Handbook of neurosurgery. Lakeland: Greenberg Graphics.
Rosenblum, W. I. (2007). Cytotoxic edema: Monitoring its magnitude and contribution to brain swelling. Journal of Neuropathology and Experimental Neurology, 66(9), 771–778.
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Tye, G., Brown, J. (2018). Cerebral Edema. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_305
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DOI: https://doi.org/10.1007/978-3-319-57111-9_305
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