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Reuptake

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  • First Online:
Encyclopedia of Clinical Neuropsychology

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Synonyms

Re-uptake; Reabsorption

Definition

Reuptake is the reabsorption of a secreted substance by the same cell that originally secreted it. It is essential in regulating the level of neurotransmitter in the synapse and therefore controls the time during which the substance is available for synaptic transmission. When a nerve releases a neurotransmitter, the neurotransmitter either travels to a receptor of a nearby cell or, in the case of reuptake, reattaches to the receptor of the cell that produced it. In this case, the neurotransmitter is taken back into the cell and recycled. The efficiency of the reuptake mechanism is often used to treat and regulate many psychological conditions that involve neurotransmitters, including depression and anxiety.

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References and Readings

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Author information

Authors and Affiliations

  1. Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA

    Chava Creque

  2. Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Stephanie A. Kolakowsky-Hayner

Authors
  1. Chava Creque
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  2. Stephanie A. Kolakowsky-Hayner
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Corresponding author

Correspondence to Chava Creque .

Editor information

Editors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, VA, USA

    Jeffrey S. Kreutzer

  2. Kessler Foundation, Pleasant Valley Way, West Orange, NJ, USA

    John DeLuca

  3. Independent Practice, Wynnewood, PA, USA

    Bruce Caplan

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© 2018 Springer International Publishing AG, part of Springer Nature

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Creque, C., Kolakowsky-Hayner, S.A. (2018). Reuptake. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1749

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