Generic Name
Rivastigmine
Brand Name
Exelon and Exelon Patch
Class
Acetylcholinesterase inhibitors, central; cholinesterase inhibitors
Proposed Mechanism(s) of Action
Reversibly binds to acetylcholinesterase and butyrylcholinesterase, thus inhibiting the breakdown of acetylcholine
Indication
Alzheimer disease and Parkinson disease
Off-Label Use
Memory disorder, mild cognitive impairment
Side Effects
Serious
Seizures and syncope
Common
Vomiting, nausea, diarrhea, appetite disturbance, weight loss, headache, dizziness, sweating, and asthenia
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References and Readings
Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.
Stahl, S. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug Interaction Effects. http://www.drugs.com/drug_interactions.html
Drug Molecule Images. http://www.worldofmolecules.com/drugs/
Free Drug Online and PDA Software. www.epocrates.com
Free Drug Online and PDA Software. www.medscape.com
Gene-Based Estimate of Drug interactions. http://mhc.daytondcs.com:8080/cgi bin/ddiD4?ver=4&task=getDrugList
Pill Identification. http://www.drugs.com/pill_identification.html
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Courtney, J.C., Akins, C., Gonzalez, E.A. (2018). Rivastigmine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1704
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1704
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