Generic Name
Pentobarbital
Brand Name
Nembutal
Class
Barbiturates; sedative/hypnotics
Proposed Mechanism(s) of Action
Enhances effectiveness of GABA transmission and activates calcium channel
Indication
Seizures, preoperative sedation, and barbiturate coma
Off-Label Use
Reduction of intracranial pressure associated with Reye’s syndrome
Side Effects
Serious
Central nervous system depression, apnea, syncope, and death
Common
Agitation, ataxia, confusion, nervousness, insomnia, anxiety, dizziness, and hypotension
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Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug interaction effects. http://www.drugs.com/drug_interactions.html
Drug molecule images. http://www.worldofmolecules.com/drugs/
Free drug online and PDA software. www.epocrates.com
Free drug online and PDA software. www.medscape.com
Gene-based estimate of drug interactions. http://mhc.daytondcs.com:8080/cgibin/ddiD4?ver=4&task=getDrugList
Pill identification. http://www.drugs.com/pill_identification.html
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Courtney, J.C., Akins, C., Gonzalez, E.A. (2018). Pentobarbital. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1690
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1690
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Publisher Name: Springer, Cham
Print ISBN: 978-3-319-57110-2
Online ISBN: 978-3-319-57111-9
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