Generic Name
Hydroxyzine
Brand Name
Atarax, and Vistaril
Class
Antihistamine
Proposed Mechanism(s) of Action
Blocks histamine type I receptors.
Indication
Anxiety, anxiety produced by organic states, pruritus (itching), premedication sedation, sedation following surgery, anxious withdrawal from medication, delirium tremens, and nausea/vomiting.
Off-Label Use
Insomnia.
Side Effects
Anticholinergic, drowsiness, involuntary motor activity, headache, hallucinations, and pruritus.
Serious
Convulsions and cardiac arrest (both rare), bronchodilation, and respirator depression.
Common
Dry mouth, sedation, and tremor.
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References and Readings
Physicians’ Desk Reference (62nd ed.). (2007). Montvale: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.
Additional Information
Drug Interaction Effects: http://www.drugs.com/drug_interactions.html.
Drug Molecule Images: http://www.worldofmolecules.com/drugs/.
Free Drug Online and PDA Software: www.epocrates.com.
Gene-Based Estimate of Drug interactions: http://mhc.daytondcs.com:8080/cgibin/ddiD4?ver=4&task=getDrugList.
Pill Identification: http://www.drugs.com/pill_identification.html.
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Gonzalez, E.A. (2018). Hydroxyzine. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1663
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DOI: https://doi.org/10.1007/978-3-319-57111-9_1663
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