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Brain Tumor

  • Living reference work entry
  • First Online:
Encyclopedia of Clinical Neuropsychology

  • 57 Accesses

Definition

An abnormal mass of tissue in which some cells (glial or non-glial) grow and multiply uncontrollably. A tumor can be benign or malignant. It is associated with damage or mutation to the TP53 gene on human chromosome 17. P53 regulates the cell cycle and functions in tumor suppression. A tumor can cause damage by increasing pressure in the brain, by shifting the brain or pushing against the skull, and by invading and damaging nerves and healthy brain tissue. Some tumors may be truly indolent in their growth, growing so slowly that they are present for an unknown length of time because symptoms are less gross and disruptive. Those that are actively growing may be more likely to present with the following symptoms, depending on tumor locus: headaches; nausea or vomiting; seizures or convulsions; difficulty in thinking, speaking, or finding words; personality changes; weakness or paralysis in one part or one side of the body; loss of balance; vision changes; confusion and...

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References and Readings

  • Levin, V. A., Leibel, S. A., & Gutin, P. H. (2001). Neoplasms of the central nervous system. In V. T. DeVita, S. Hellman, & S. A. Rosenberg (Eds.), Cancer: Principles and practice of oncology (pp. 2100–2160). Philadelphia: Lippincott, Williams, & Wilkins.

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  • Price, T. R. P., Goetz, K. L., & Lovell, M. R. (2007). Neuropsychiatric aspects of brain tumors. In S. C. Yudofsky & R. E. Hales (Eds.), The American Psychiatric Publishing textbook of neuropsychiatry and behavioral neurosciences (5th ed., pp. 735–764). Washington, DC: American Psychiatric Association.

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Author information

Authors and Affiliations

  1. Department of Psychiatry & Human Behavior, Brown University, Box G-BH, Providence, RI, 02912, USA

    Ethan Moitra

  2. Drexel University, Philadelphia, PA, 19104, USA

    Daniel Smith

Authors
  1. Ethan Moitra
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  2. Daniel Smith
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Corresponding author

Correspondence to Ethan Moitra .

Editor information

Editors and Affiliations

  1. Richmond, Virgin Islands, USA

    Jeffrey Kreutzer

  2. Kessler Foundation , West Orange, New Jersey, USA

    John DeLuca

  3. Suite 200 , Wynnewood, Pennsylvania, USA

    Bruce Caplan

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© 2017 Springer International Publishing AG

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Moitra, E., Smith, D. (2017). Brain Tumor. In: Kreutzer, J., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-56782-2_94-3

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  • DOI: https://doi.org/10.1007/978-3-319-56782-2_94-3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-56782-2

  • Online ISBN: 978-3-319-56782-2

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