Encyclopedia of Clinical Neuropsychology

Living Edition
| Editors: Jeffrey Kreutzer, John DeLuca, Bruce Caplan

Sjogren’s Syndrome

Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-56782-2_574-3

Short Description

Sjogren’s Syndrome (SS) is a chronic lymphoproliferative, autoimmune disease that has been found primarily among postmenopausal women. SS inflames tear ducts and salivary glands (Meijer et al. 2007) and causes disturbances of Y lymphocytes, B lymphocytes, and exocrine glands, essentially causing one’s white blood cells to “attack” the individual’s body (Hansen et al. 2007).

Categorization

There are two categories of SS. The primary type is a chronic autoimmune disorder marked with dryness of the mouth, eyes and other mucous membranes (Goransson et al. 2006). Secondary SS occurs in individuals diagnosed with other connective tissue disorders such as rheumatoid arthritis, progressive systemic sclerosis, and systemic lupus erythematosus.

Epidemiology

SS affects all populations worldwide. The disease is most prevalent in people in their forties and fifties and has a 9:1 female to male ratio (Meijer et al. 2007). The prevalence of the disease is reported to be 0.2% of the...

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References and Readings

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  3. Hansen, A., Lipsky, P. E., & Dorner, T. (2007). B cells in lymphoproliferation in chronic inflammatory rheumatic disorders. Nature Clinical Practice Rheumatology, 3(10), 561–569.CrossRefPubMedGoogle Scholar
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  7. Vitali, C., Bombardieri, S., Jonsson, R., Moutsopoulos, H. M., Alexander, E. L., Carsons, S. E., Daniels, T. E., Fox, P. C., Fox, R. I., Kassan, S. S., Pillemer, S. R., Talal, N., Weisman, M. H., & European Study Group on Classification Criteria for Sjogren’s Syndrome. (2002). Classification criteria for Sjogren’s syndrome: A revised version of the European criteria proposed by the American-European consensus Group. Annals of the Rheumatic Diseases, 61(6), 554.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of Neurobiology and AnatomyWake Forest School of MedicineWinston-SalemUSA