Skip to main content

Absolute and Relative Bioavailability

Abstract

Attaining desired blood drug concentration and, consequently, augmenting the bioavailability of poorly absorbed drugs have always been an essential aspect for the pharmaceutical agency. The achievement of this target gives positive economic benefits as reducing drug dosage and medical impacts in decreasing toxicity and bacterial resistance in case of antimicrobials. Various factors may reduce the availability of drugs. There are numerous ways to estimate bioavailability. Various software’s models have been developed to simplify such analyses. The newly developed programs should provide a range of modules for pharmacokinetic and pharmacodynamic analysis with a more user-friendly interface.

This is a preview of subscription content, log in via an institution.

References and Further Reading

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Khaled Abo-EL-Sooud .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Abo-EL-Sooud, K. (2018). Absolute and Relative Bioavailability. In: Hock, F., Gralinski, M. (eds) Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Springer, Cham. https://doi.org/10.1007/978-3-319-56637-5_16-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-56637-5_16-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-56637-5

  • Online ISBN: 978-3-319-56637-5

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics

Chapter history

  1. Latest

    Absolute and Relative Bioavailability
    Published:
    03 May 2018

    DOI: https://doi.org/10.1007/978-3-319-56637-5_16-2

  2. Original

    Absolute and Relative Bioavailability
    Published:
    06 March 2018

    DOI: https://doi.org/10.1007/978-3-319-56637-5_16-1