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Are Myristica fragrans L. (Myristicaceae) and Its Phytochemicals Useful for Human Health?

  • Monica Rosa Loizzo
  • Vincenzo Sicari
  • Jianbo Xiao
  • Rosa Tundis
Living reference work entry
Part of the Reference Series in Phytochemistry book series (RSP)

Abstract

From Myristica fragrans L. (Myristicaceae) two spices, nutmeg and mace, were obtained. This plant is traditionally used in China, India, and African countries for the treatment of several diseases, such as decreased appetite, diarrhea, muscle spasm, rheumatism, etc. Recently, M. fragrans has been investigated for antioxidant, anticonvulsant, analgesic, anti-inflammatory, antidiabetic, hypolipidemic and hypocholesterolemic, antibacterial, and antifungal potential.

A perusal analysis of literature evidenced that M. fragrans deserves more attention by scientific community to explore its full range of bioactivity in the welfare of the society especially in emergent Countries.

Keywords

Myristica fragrans Chemical profile Bioactivity Toxicity 

List of Abbreviations

5-HT

Serotonin

AChE

Acetylcholinesterase

AMPK

AMP-activated protein kinase

BChE

Butyrylcholinesterase

DM

Diabetes mellitus

GABA

γ-Aminobutyric acid

IL

Interleukin

LDH-A

Lactate dehydrogenase

MCP

Monocyte chemotactic protein

MIP

Macrophage inflammatory protein

NO

Nitric oxide

PAS

Peripheral anionic site

THF

Tetrahydrofuran mixture

Notes

Conflicts of Interest

The authors declare no conflicts of interest.

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Monica Rosa Loizzo
    • 1
  • Vincenzo Sicari
    • 2
  • Jianbo Xiao
    • 3
    • 4
  • Rosa Tundis
    • 1
  1. 1.Department of Pharmacy, Health and Nutritional SciencesUniversity of CalabriaRende, CosenzaItaly
  2. 2.Department of Agricultural ScienceMediterranean University of Reggio CalabriaReggio, CalabriaItaly
  3. 3.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese MedicineMacau UniversityTaipaMacau
  4. 4.Institut für Pharmazie und LebensmittelchemieUniversität WürzburgWürzburgGermany

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