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Yarrowia lipolytica as a Cell Factory for Oleochemical Biotechnology

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Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals

Part of the book series: Handbook of Hydrocarbon and Lipid Microbiology ((HHLM))

Abstract

Yarrowia lipolytica is one of the more popularly studied nonconventional yeasts due to its innate abilities to accumulate lipids and utilize diverse carbon substrates. In this chapter, we discuss several recent oleochemical applications of Y. lipolytica that are currently under investigation. These applications include the production of single cell oil, various modified fatty acids, citric acid, lipase, and other compounds. Additionally, we cover the lipophilic nature of Y. lipolytica in catabolic applications including bioremediation of oil-polluted water and soil. Finally, we address future outlooks for the cost-effective production of these chemicals in Y. lipolytica.

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Acknowledgments

This work was funded by the Welch Foundation under Grant F-1753 and the Office of Naval Research under Grant N00014-15-1-2785.

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Authors and Affiliations

  1. McKetta Department of Chemical Engineering, The University of Texas at Austin, 200 E Dean Keeton St. Stop C0400, Austin, TX, 78712, USA

    Kelly A. Markham, Lauren Cordova, Andrew Hill & Hal S. Alper

  2. Institute for Cellular and Molecular Biology, The University of Texas at Austin, 2500 Speedway Avenue, Austin, TX, 78712, USA

    Hal S. Alper

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  1. Kelly A. Markham
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  2. Lauren Cordova
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  4. Hal S. Alper
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Correspondence to Hal S. Alper .

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  1. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea (Republic of)

    Sang Yup Lee

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Markham, K.A., Cordova, L., Hill, A., Alper, H.S. (2017). Yarrowia lipolytica as a Cell Factory for Oleochemical Biotechnology. In: Lee, S. (eds) Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals. Handbook of Hydrocarbon and Lipid Microbiology . Springer, Cham. https://doi.org/10.1007/978-3-319-50436-0_223

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