Yarrowia lipolytica as a Cell Factory for Oleochemical Biotechnology

  • Kelly A. Markham
  • Lauren Cordova
  • Andrew Hill
  • Hal S. Alper
Reference work entry
Part of the Handbook of Hydrocarbon and Lipid Microbiology book series (HHLM)


Yarrowia lipolytica is one of the more popularly studied nonconventional yeasts due to its innate abilities to accumulate lipids and utilize diverse carbon substrates. In this chapter, we discuss several recent oleochemical applications of Y. lipolytica that are currently under investigation. These applications include the production of single cell oil, various modified fatty acids, citric acid, lipase, and other compounds. Additionally, we cover the lipophilic nature of Y. lipolytica in catabolic applications including bioremediation of oil-polluted water and soil. Finally, we address future outlooks for the cost-effective production of these chemicals in Y. lipolytica.



This work was funded by the Welch Foundation under Grant F-1753 and the Office of Naval Research under Grant N00014-15-1-2785.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2017

Authors and Affiliations

  • Kelly A. Markham
    • 1
  • Lauren Cordova
    • 1
  • Andrew Hill
    • 1
  • Hal S. Alper
    • 1
    • 2
  1. 1.McKetta Department of Chemical EngineeringThe University of Texas at AustinAustinUSA
  2. 2.Institute for Cellular and Molecular BiologyThe University of Texas at AustinAustinUSA

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