Microbial Production of Isoprenoids

  • J. Wong
  • L. Rios-Solis
  • J. D. Keasling
Reference work entry
Part of the Handbook of Hydrocarbon and Lipid Microbiology book series (HHLM)


Isoprenoids are among the most diverse groups of compounds synthesized by biological systems; it has been estimated that there are approximately 30,000–50,000 known isoprenoids, which include the terpenoids and carotenoids. Isoprenoids are important in maintaining membrane fluidity, electron transport, protein prenylation, and cellular and organismal development and in controlling pests. Many isoprenoids have found application as fragrances and essential oils, pharmaceuticals, specialty and commodity chemicals, and most recently biofuels. To make all of these applications of isoprenoids possible, their production in microbial hosts is essential. Recently, there has been much progress in producing these complex hydrocarbons in both Escherichia coli and Saccharomyces cerevisiae. In this chapter, we review recent progress in this area.


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© Springer International Publishing AG, part of Springer Nature 2017

Authors and Affiliations

  1. 1.Joint BioEnergy InstituteEmeryvilleUSA
  2. 2.Departments of Chemical Engineering and BioengineeringUniversity of California at BerkeleyBerkeleyUSA
  3. 3.Physical Biosciences DivisionLawrence Berkeley National LaboratoryBerkeleyUSA

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