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Hypopigmentary Skin Disorders

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Atlas of Dermatology, Dermatopathology and Venereology

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Abstract

This chapter provides a concise overview of melanogenesis, the suggested clinical approach to hypomelanosis, and subsequent characterization of a multitude of hypopigmentary disorders. Classification of these entities is broadly designated as either occurring in childhood (especially genodermatoses) or acquired. Further subclassification denotes those presenting with generalized versus localized involvement. Each clinical entity includes a brief etiology, pathogenesis, pertinent extracutaneous symptoms, diagnostic findings, prognosis, treatment, and possible differential diagnoses. For many of these processes, a diagnostic impression may be formulated on the sole basis of history and physical examination; a biopsy may be unwarranted.

The corresponding clinical and microscopic images represent the most classic or pathognomonic features. Many factors including (but not limited to) abnormal presentation, chronicity, overlapping characteristics, or lack of definitive findings have the potential to preclude accurate diagnostic interpretation.

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Authors and Affiliations

  1. Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA

    Bre Ana M. David, Jacob Curley, Jonathan Davick & Nicholas Jaeger

  2. Department of Dermatology, University of Virginia Health System, Charlottesville, VA, USA

    Richard Flowers, Vernon Forrester, Darren Guffey, Katherine Gresham, Jade Kimball Kindley, Patrick Carr, Merrick Kozak & Gabriella Melson

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Correspondence to Bre Ana M. David .

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  1. Department of Pathology, Univ of Rochester School of Med, Rochester, NY, USA

    Bruce Smoller

  2. Khorramshahr, Iran

    Nooshin Bagherani

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David, B.A.M. et al. (2020). Hypopigmentary Skin Disorders. In: Smoller, B., Bagherani, N. (eds) Atlas of Dermatology, Dermatopathology and Venereology . Springer, Cham. https://doi.org/10.1007/978-3-319-45134-3_97-1

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  • DOI: https://doi.org/10.1007/978-3-319-45134-3_97-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-45134-3

  • Online ISBN: 978-3-319-45134-3

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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