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Principles of Endocrine Diseases

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Book cover Principles of Endocrinology and Hormone Action

Part of the book series: Endocrinology ((ENDOCR))

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Abstract

Broadly defined, endocrine diseases can be defined as disorders of (1) hormone deficiency, (2) hormone excess, (3) hormone resistance, (4) defects in transport proteins, and (5) benign or malignant tumors of the hormone-producing glands. These diseases can, in part, be caused by mutations in single genes (monogenic disorders), others result from the interaction of genetic predisposition and lifestyle factors (complex or multifactorial disorders), some are solely due to environmental factors (nutritional iodine deficiency), and several disorders are the result of a dysregulated immune system (autoimmune disorders). A detailed understanding of the underlying pathophysiology is of significant importance because it can provide means for an accurate diagnosis, therapy and intervention, and the development of novel therapeutic modalities.

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Author information

Authors and Affiliations

  1. Division of Endocrinology, Metabolism and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Tarry 15, 303 East Chicago Avenue, Chicago, IL, 60611, USA

    Elizabeth Lowden & Peter Kopp

Authors
  1. Elizabeth Lowden
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  2. Peter Kopp
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Corresponding author

Correspondence to Peter Kopp .

Editor information

Editors and Affiliations

  1. Magna Graecia University, Catanzaro, Italy

    Antonino Belfiore

  2. Icahn School of Medicine at Mt. Sinai, New York, New York, USA

    Derek LeRoith

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Lowden, E., Kopp, P. (2018). Principles of Endocrine Diseases. In: Belfiore, A., LeRoith, D. (eds) Principles of Endocrinology and Hormone Action. Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-319-44675-2_28

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  • DOI: https://doi.org/10.1007/978-3-319-44675-2_28

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44674-5

  • Online ISBN: 978-3-319-44675-2

  • eBook Packages: MedicineReference Module Medicine

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