Glomus Tumor, Gastrointestinal
Glomangioma; Glomangiomatosis; Glomangiomyoma; Glomangiopericytoma; Glomangiosarcoma; Malignant glomus tumor; Symplastic glomus tumor
Glomus tumors are mesenchymal neoplasm comprising cells that resemble the modified smooth muscle cells of the normal glomus body. The glomus body is a specialized form of arteriovenous anastomosis which is involved in temperature regulation. There is a central coiled canal known as Sucquet-Hoyer canal which is lined by plump endothelial cells. This is surrounded by longitudinal and circular muscle fibers containing epithelial appearing glomus cells.
Glomus tumors are rare in the gastrointestinal tract. The incidence of glomus tumor is estimated to be 1% of that of gastrointestinal tumors.
The median age of gastrointestinal glomus tumors is 48–55 years (range 19–90 years) (Kang et al. 2012).
Gastrointestinal glomus tumors predominate in females (∼ 3:1) (Miettinnen et al. 2010).
References and Further Reading
- Miettinnen, M. (2010). Glomus tumor, sinonasal haemangiopericytoma, and myopericytoma. In M. Miettinen (Ed.), Modern soft tissue pathology: Tumors and non-neoplastic conditions (pp. 648–656). Cambridge: Cambridge University Press.Google Scholar
- Miettinnen, M., Fletcher, C. D. M., Kindblom, L.-G., & Tsui, W. M. S. (2010). Mesenchymal tumours of the oesophagus, stomach, small intestine, colon and rectum. In F. T. Bosman, F. Carneiro, R. H. Hruban, & N. E. Theise (Eds.), WHO classification of tumours of the digestive system (p. 76). Lyon: International Agency for Research on Cancer (IARC).Google Scholar