When blood flow in the rich gastric vasculature is disrupted, ischemic damage to the stomach occurs. There is a wide array of causes associated with this disruption, and the severity of the effects is related to the underlying cause. The most commonly present risk factors are the association of diffuse and severe atherosclerosis, hypertension, and smoking (Fenoglio-Preiser et al. 2008). The mechanic impairment of blood flow by the presence of a volvulus or previous surgery is also listed as a cause of gastric ischemia. Furthermore, systemic alterations in circulation (such as shock or trauma induced hypotension or hypoxemia) eventually affect mesenteric blood flow. Thrombus or even emboli from the aorta may lodge in the arteries supplying the gastric wall and cause ischemic damage. A recently recognized cause of ischemic gastritis is the embolization, to the vasculature of the stomach, of radiologically placed beads used to perform embolization of...
References and Further Reading
- Fenoglio-Preiser, C. M., Noffsinger, A. E., Stemmermann, G. N., Lantz, P. E., & Isaacson, P. G. (2008). The nonneoplastic stomach. In J. McGouh & J. Pine (Eds.), Gastrointestinal pathology an atlas and text (pp. 167–168). Philadelphia: Lippincott Williams & Wilkins.Google Scholar
- Mitchell, K. A. (2009). Vascular disorders of the GI tract. In R. Odze & J. Goldblum (Eds.), Surgical pathology of the GI tract, liver, biliary tract and pancreas. Philadelphia: Saunders.Google Scholar