Adenosquamous Carcinoma, Upper GI Tract
There are no current synonyms for this neoplasm. Historically, it has been often confounded with mucoepidermoid carcinoma.
A malignant epithelial neoplasm that has mixed elements of glandular and squamous cell differentiation, which remains clearly distinguishable within the tumor.
Adenosquamous carcinoma (ASC) is a rare disease. No worldwide incidence data is available. In the largest published series, it represented 1.0% of all esophageal cancers.
In the largest published series, patients’ age range from 51 to 85 years, with a mean age of 64 years.
The disease is more frequent in males.
Adenosquamous carcinoma is somewhat more frequent in the middle and lower thirds of the esophagus.
Surgery is the treatment of choice and can be followed by radiotherapy. This particular histological type does not change the usual treatment for esophageal carcinomas.
ASC seems to have a better prognosis than conventional...