Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari


  • Gert De HertoghEmail author
Reference work entry


Shiga bacillus dysentery; Shigella dysentery


Before defining shigellosis, it is necessary to clarify the meaning of a few terms commonly employed in the gastroenterology clinic. Diarrhea means the passage of three or more unformed stools per day. It can be a symptom of colitis, which is a disease characterized by the presence of a histological lesion: colonic inflammation. The inflammatory process may be limited to the mucosa or extend to the deeper layers of the bowel wall. The diagnosis of colitis can be established when, in a patient with diarrhea, one or more of the following features are present: (1) passage of multiple small-volume stools containing blood and mucus (this symptom is called “dysentery”), (2) positive markers for colonic inflammation in the stools (leukocytes adherent to the mucus on microscopic examination, positive fecal lactoferrin or calprotectin test), and (3) colonoscopy showing mucosal inflammation. Colitis is classified as acute when it...

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References and Further Reading

  1. Anand, B. S., Malhotra, V., Bhattacharya, S. K., et al. (1986). Rectal histology in acute bacillary dysentery. Gastroenterology, 90, 654–660.CrossRefGoogle Scholar
  2. DuPont, H. L. (2012). Approach to the patient with infectious colitis. Current Opinion in Gastroenterology, 28, 39–46.CrossRefGoogle Scholar
  3. Kumar, N. B., Nostrant, T. T., & Appelman, H. D. (1982). The histopathologic spectrum of acute self-limited colitis (acute infectious-type colitis). The American Journal of Surgical Pathology, 6, 523–529.CrossRefGoogle Scholar
  4. Sachdev, H. P., Chadha, V., Malhotra, V., et al. (1993). Rectal histopathology in endemic Shigella and Salmonella diarrhea. Journal of Pediatric Gastroenterology and Nutrition, 16, 33–38.CrossRefGoogle Scholar
  5. Talan, D., Moran, G. J., Newdow, M., et al. (2001). Etiology of bloody diarrhea among patients presenting to United States emergency departments: Prevalence of Escherichia coli O157:H7 and other enteropathogens. Clinical Infectious Diseases, 32, 573–580.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Department of PathologyPathologische Ontleedkunde, UZ LeuvenLeuvenBelgium