Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari


  • Anne Jouret-MourinEmail author
Reference work entry


Typhoid fever


Salmonella is a gram-negative bacteria which invades the epithelium of the ileum and colon and is divided into two forms of disease affecting the gastrointestinal tract: typhoid and non-typhoid species. Salmonella typhi is the most common cause agent of typhoid fever; S. paratyphi can cause similar clinical symptoms. Non-typhoid species including S. enteritidis, S. typhimurium, S. javania, S muenchen, S. anatum, S. Newport, S. oranienburg are generally associated with self-limited gastroenteritis or enterocolitis. The infective dose is relatively low; approximately 102–103 organisms may cause human disease.

Salmonella infection is a global health problem. It is transmitted through contaminated food and water and is prevalent in the developing countries. Salmonellainfection is also an important cause of sporadic food poisoning in developed countries and traveler’s diarrhea. It has been steadily increasing steadily during the past decade. More than 95%...

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References and Further Reading

  1. Boyd, J. F. (1985). Pathology of the alimentary tract in Salmonella typhimurium food poisoning. Gut, 26, 935–944.CrossRefGoogle Scholar
  2. Dagash, M., et al. (1997). Transient radiological and colonoscopic features of IBD in a patient with severe Salmonella gastroenteritis. The American Journal of Gastroenterology, 92, 349–351.PubMedGoogle Scholar
  3. Lamps, L. W. (2007). Infective disorders of the gastrointestinal tract. Histopathology, 50, 55–63.CrossRefGoogle Scholar
  4. McGovern, V. J., et al. (1979). Pathology of Salmonella colitis. The American Journal of Surgical Pathology, 3, 483–490.CrossRefGoogle Scholar
  5. Lamps, L. W. (2009). Salmonella species in surgical pathology of the gastrointestinal system: Bacterial, fungal, viral and parasitic infections (pp. 27–31). New York: Springer.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Department of PathologyCliniques Universitaires St. Luc, UCLBrusselsBelgium