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Pathology of the Gastrointestinal Tract pp 523–528Cite as

Mucocele, Appendix

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Appendiceal mucinous cystadenoma; Low-grade appendiceal mucinous neoplasm (LAMN); Low-grade appendiceal mucinous tumor; Mucosal hyperplasia; Retention cyst; Retention mucocele

Definition

Appendiceal mucocele is an obstructive dilatation of the appendix caused by intraluminal accumulation of mucoid material (Fig. 1a, b). This purely descriptive term was first coined by Rokitansky in 1855, and does not constitute a pathological diagnosis. The density of goblet cells is far greater within the epithelium of the appendix than within the colon. As a result, the most frequent appendiceal epithelial tumors are mucinous and begin as mucoceles.

Mucocele, Appendix, Fig. 1
figure 1230 figure 1230

(a) The appendix is dilated and thin walled. The distal portion of the appendix is more dilated than the proximal portion. There is no perforation. (b) The appendix is opened lengthwise: a gelatinous material is present in the lumen

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References and Further Reading

  • Carr, N. J., & Sobin, L. H. (2010). Tumours of the appendix. In F. T. Bosman, F. Carneiro, R. H. Hruban, & N. D. Theise (Eds.), WHO classification of tumours of the digestive system (pp. 122–125). Lyon: IARC Press.

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  • Carr, N. J., Finch, J., Ilesley, I. C., et al. (2012). Pathology and prognosis in pseudomyxoma peritonei: A review of 274 cases. Journal of Clinical Pathology, 65, 919–923.

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  • Chua, T. C., Moran, B. J., Sugarbaker, P. H., et al. (2012). Early- and long-term outcome data of patients with pseudomyxoma peritone from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Journal of Clinical Oncology, 20, 2449–2456.

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  • Higa, E., Rosai, J., & Pizzimbono, C. A. (1973). Mucosal hyperplasia, mucinous cystadenoma and mucinous cystadenocarcinoma of the appendix: A re-evaluation of appendiceal “mucocele”. Cancer, 32, 1525–1541.

    Article  CAS  Google Scholar 

  • Smeenk, R. M., van Velthuysen, M. L., Verwaal, V. J., & Zoetmulder, F. A. (2008). Appendiceal neoplasms and pseudomyxoma peritonei: A population-based study. European Journal of Surgical Oncology, 34, 196–201.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Hôpital Saint-Antoine, Service d’Anatomie Pathologique, AP-HP, Hôpitaux Universitaires de l’Est Parisien, 184 rue du Faubourg Saint-Antoine, 75 012, Paris, France

    Magali Svrcek

Authors
  1. Magali Svrcek
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Corresponding author

Correspondence to Magali Svrcek .

Editor information

Editors and Affiliations

  1. Faculty of Medicine of Porto University, Centro Hospitalar São João and Ipatimup/i3S, Porto, Portugal

    Fátima Carneiro

  2. Serviço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa de Francisco Gentil, Lisbon, Portugal

    Paula Chaves

  3. Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal

    Paula Chaves

  4. Department of Pathology, Ankara University Medical School, Sihhiye, Ankara, Turkey

    Arzu Ensari

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Svrcek, M. (2017). Mucocele, Appendix. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1514

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  • DOI: https://doi.org/10.1007/978-3-319-40560-5_1514

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40559-9

  • Online ISBN: 978-3-319-40560-5

  • eBook Packages: MedicineReference Module Medicine

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