Advertisement

Beekeepers

  • Randolf Brehler
Living reference work entry

Abstract

Occupational skin diseases are reported only in single beekeepers.

Principally beekeepers are at high risk for the development of immediate-type allergy to bee venom; sensitization prevalence is in the range of 30–60%.

In some cases, IgE-mediated allergy was reported against honey, pollens, royal jelly, mold fungi, and bee body allergens.

Important contact allergens are propolis, beeswax, royal jelly, and essential oils.

Potential irritants are chemicals used for the treatment of bee infections with parasitic mites and mold fungi.

Keywords

Beekeeper Bee venom Propolis Beeswax Rojal jelly Honey Essential oils Anaphylaxis Immediate-type allergy Contact dermatitis 

References

  1. Aguiar R, Duarte FC, Mendes A, Bartolomé B, Barbosa MP (2017) Anaphylaxis caused by honey: a case report. Asia Pac Allergy 7:48–50CrossRefGoogle Scholar
  2. Asero R, Mistrello G, Roncarolo D, Amato S (2008) Respiratory and skin allergy to Galleria mellonella (bee moth). Int Arch Allergy Immunol 145:340–342CrossRefGoogle Scholar
  3. Athanasiadis GI, Pfab F, Klein A, Braun-Falco M, Ring J, Ollert M (2007) Erythema multiforme due to contact with laurel oil. Contact Dermatitis 57:116–118CrossRefGoogle Scholar
  4. Blank S, Etzold S, Darsow U, Schiener M, Eberlein B, Russkamp D, Wolf S, Graessel A, Biedermann T, Ollert M, Schmidt-Weber CB (2017) Component-resolved evaluation of the content of major allergens in therapeutic extracts for specific immunotherapy of honeybee venom allergy. Hum Vaccin Immunother 11:1–8.  https://doi.org/10.1080/21645515.2017.1323603. [Epub ahead of print]CrossRefGoogle Scholar
  5. Bonifazi F, Jutel M, Biló BM, Birnbaum J, Muller U, EAACI Interest Group on Insect Venom Hypersensitivity (2005) Prevention and treatment of hymenoptera venom allergy: guidelines for clinical practice. Allergy 60(12):1459–1470CrossRefGoogle Scholar
  6. Bousquet J, Coulomb Y, Robinet-Levy M, Michel FB (1982) Clinical and immunological surveys in beekeepers. Clin Allergy 12:331–342CrossRefGoogle Scholar
  7. Bousquet J, Müller UR, Dreborg S, Jarisch R, Malling HJ, Mosbech H, Urbanek R, Youlten L (1987) Immunotherapy with Hymenoptera venoms. Position paper of the working group on immunotherapy of the European academy of allergy and clinical immunology. Allergy 42:401–413CrossRefGoogle Scholar
  8. Cifuentes L (2015) Allergy to honeybee ... not only stings. Curr Opin Allergy Clin Immunol 15:364–368CrossRefGoogle Scholar
  9. Damiani N, Gende LB, Bailac P, Marcangeli JA, Eguaras MJ (2009) Acaricidal and insecticidal activity of essential oils on Varroa destructor (Acari: Varroidae) and Apis mellifera (Hymenoptera: Apidae). Parasitol Res 106:145–152CrossRefGoogle Scholar
  10. Eich-Wanger C, Müller UR (1998) Bee sting allergy in beekeepers. Clin Exp Allergy 28:1292–8CrossRefGoogle Scholar
  11. Frick M, Fischer J, Helbling A, Ruëff F, Wieczorek D, Ollert M, Pfützner W, Müller S, Huss-Marp J, Dorn B, Biedermann T, Lidholm J, Ruecker G, Bantleon F, Miehe M, Spillner E, Jakob T (2016) Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy. J Allergy Clin Immunol 138:1663–1671CrossRefGoogle Scholar
  12. Fuiano N, Incorvaia C, Riario-Sforza GG, Casino G (2006) Anaphylaxis to honey in pollinosis to mugwort: a case report. Eur Ann Allergy Clin Immunol 38:364–365PubMedGoogle Scholar
  13. Giusti F, Miglietta R, Pepe P et al (2004) Sensitization to propolis in 1255 children undergoing patch testing. Contact Dermatitis 51:255–258CrossRefGoogle Scholar
  14. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, Feo Brito JF, Alfaya Arias T, Galindo Bonilla PA, Ledesma Fernandez A, García Rodríguez R (2016) Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol 117:102–103CrossRefGoogle Scholar
  15. Gulbahar O, Ozturk G, Erdem N, Kazandi AC, Kokuludag A (2005) Psoriasiform contact dermatitis due to propolis in a beekeeper. Ann Allergy Asthma Immunol 94:509–511CrossRefGoogle Scholar
  16. Hagvall L, Sköld M, Bråred-Christensson J, Börje A, Karlberg AT (2008) Lavender oil lacks natural protection against autoxidation, forming strong contact allergens on air exposure. Contact Dermatitis 59:143–150CrossRefGoogle Scholar
  17. Hausen BM (2005) Evaluation of the main contact allergens in propolis (1995 to 2005). Dermatitis 16:127–129PubMedGoogle Scholar
  18. Hausen BM, Evers P, Stuwe HT et al (1992) Propolis allergy (IV). Studies with further sensitizers from propolis and constituents common to propolis, poplar buds and balsam of Peru. Contact Dermatitis 26:34–44CrossRefGoogle Scholar
  19. Helbling A, Peter C, Berchtold E, Bogdanov S, Müller U (1992) Allergy to honey: relation to pollen and honey bee allergy. Allergy 47:41–49CrossRefGoogle Scholar
  20. Hellner M, Winter D, von Georgi R, Münstedt K (2008) Apitherapy: usage and experience in German beekeepers. Evid Based Complement Alternat Med 5:475–479CrossRefGoogle Scholar
  21. Katayama M, Aoki M, Kawana S (2008) Case of anaphylaxis caused by ingestion of royal jelly. J Dermatol 35:222–224CrossRefGoogle Scholar
  22. Katayama M, Inomata N, Inagawa N, Fukuro S, Aihara M (2016) A case of contact urticaria syndrome stage 3 after honey ingestion, induced by epicutaneous sensitization during skin care with honey. Contact Dermatitis 74:189–191CrossRefGoogle Scholar
  23. Leung R, Ho A, Chan J, Choy D, Lai CK (1997) Royal jelly consumption and hypersensitivity in the community. Clin Exp Allergy 27:333–336CrossRefGoogle Scholar
  24. Li LS, Guan K (2016) Occupational asthma caused by inhalable royal jelly and its cross-reactivity with honeybee venom. Chin Med J 129:2888–2889CrossRefGoogle Scholar
  25. Lombardi C, Senna GE, Gatti B, Feligioni M, Riva G, Bonadonna P, Dama AR, Canonica GW, Passalacqua G (1998) Allergic reactions to honey and royal jelly and their relationship with sensitization to compositae. Allergol Immunopathol (Madr) 26:288–290Google Scholar
  26. Lorenzi S, Placucci F, Vincenzi C, Bardazzi F, Tosti A (1995) Allergic contact dermatitis due to thymol. Contact Dermatitis 33:439–440CrossRefGoogle Scholar
  27. Matos D, Serrano P, Menezes Brandão F (2015) A case of allergic contact dermatitis caused by propolis-enriched honey. Contact Dermatitis 72:59–60CrossRefGoogle Scholar
  28. Mueller U, Mosbech H (1993) Position paper. Immunotherapy with Hymenoptera venoms. EAACI. Allergy 48:36–46Google Scholar
  29. Müller UR (2005) Bee venom allergy in beekeepers and their family members. Curr Opin Allergy Clin Immunol 5:343–347CrossRefGoogle Scholar
  30. Münstedt K, Hellner M, Hackethal A, Winter D, von Georgi R (2007) Contact allergy to propolis in beekeepers. Allergol Immunopathol (Madr) 35:95–100CrossRefGoogle Scholar
  31. Nyman G, Hagvall L (2016) A case of allergic contact cheilitis caused by propolis and honey. Contact Dermatitis 74:186–187CrossRefGoogle Scholar
  32. Ollert M, Blank S (2015) Anaphylaxis to insect venom allergens: role of molecular diagnostics. Curr Allergy Asthma Rep 15:26CrossRefGoogle Scholar
  33. Przybilla B, Ruëff F (2010) Hymenoptera venom allergy. J Dtsch Dermatol Ges 8:114–127CrossRefGoogle Scholar
  34. Przybilla B, Ruëff F, Fuchs T, Pfeiffer C, Rakoski J, Stolz W, Vieluf D (2004) Insektengiftallergie. Allergo J 13:186–190. http://www.uni-duesseldorf.de/AWMF/ll/061-020.htmCrossRefGoogle Scholar
  35. Rajpara S, Wilkinson MS, King CM, Gawkrodger DJ, English JS, Statham BN, Green C, Sansom JE, Chowdhury MM, Horne HL, Ormerod AD (2009) The importance of propolis in patch testing–a multicentre survey. Contact Dermatitis 61:287–290CrossRefGoogle Scholar
  36. Rosmilah M, Shahnaz M, Patel G, Lock J, Rahman D, Masita A, Noormalin A (2008) Characterization of major allergens of royal jelly Apis mellifera. Trop Biomed 25:243–251PubMedGoogle Scholar
  37. Rudeschko O, Machnik A, Dörfelt H, Kaatz HH, Schlott B, Kinne RW (2004) A novel inhalation allergen present in the working environment of beekeepers. Allergy 59:332–337CrossRefGoogle Scholar
  38. Sammataro D, Gerson U, Needham G (2000) Parasitic mites of honey bees: life history, implications, and impact. Annu Rev Entomol 45:519–548CrossRefGoogle Scholar
  39. Schaller M, Korting HC (1995) Allergic airborne contact dermatitis from essential oils used in aromatherapy. Clin Exp Dermatol 20:143–145CrossRefGoogle Scholar
  40. Sugiura M, Hayakawa R, Kato Y, Sugiura K, Hashimoto R (2000) Results of patch testing with lavender oil in Japan. Contact Dermatitis 43:157–160CrossRefGoogle Scholar
  41. Takahashi M, Matsuo I, Ohkido M (1983) Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 9:452–455CrossRefGoogle Scholar
  42. Van Engelsdorp D, Underwood RM, Cox-Foster DL (2008) Short-term fumigation of honey bee (Hymenoptera: Apidae) colonies with formic and acetic acids for the control of Varroa destructor (Acari: Varroidae). J Econ Entomol 101:256–264CrossRefGoogle Scholar
  43. Villalta D, Martelli P, Mistrello G, Roncarolo D, Zanoni D (2004) Bee moth (Galleria mellonella) allergic reactions are caused by several thermolabile antigens. Allergy 59:1002–1005CrossRefGoogle Scholar
  44. Walgrave SE, Warshaw EM, Glesne LA (2005) Allergic contact dermatitis from propolis. Dermatitis 16: 209–215PubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of DermatologyUniversity Hospital MünsterMünsterGermany

Personalised recommendations