Cerebrospinal Fluid, Normal Cytology

Definition

The evaluation of CSF has diagnostic purposes in inflammatory processes (infectious) and the detection of neoplasias. Produced by the choroid plexus in the ventricles via ultrafiltration of plasma, it is reabsorbed through the villi arachnoid being produced about 500 ml/24 h. Leptomeningeal and ependymal cells are rarely observed in its analysis uses the cytological aspects found the patient’s age, medical history, and results of laboratory tests of interest. Most samples are originate from lumbar puncture, but can be obtained from the ventricles. It should indicate the location of the sample, because the cellular components are distinct The prepared material must be obtained through concentration method. It is recommended that preparations be stained by Papanicolaou and Giemsa. The sensitivity of CSF for detecting malignance is about 60%, the specificity is high, and false-positive diagnoses are around 2–3%.

Clinical Features

• Incidence

  Over 90% of CSF cytology are negative...