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Craniopharyngioma

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Abstract

The term craniopharyngioma was coined 85 years ago by Frazier and Alpers and initially described by Cushing as a “baffling problem.” This problem although better understood remains baffling. The optimal treatment which will provide good quality longevity to these children remains to be fully defined. A multimodality approach determined by the age of the patient, the cystic or solid nature of the tumor, and the size of the tumor at presentation is necessary in the armamentarium of the practitioner treating patients with this tumor. We review the epidemiology, the clinical presentation, and the treatment modalities for both cystic and solid tumors with their complications and efficacies in this chapter. Emerging therapeutic approaches based on molecular studies and strategies targeting specific pathways offer promise that the armamentarium available to treat this tumor in young children will broaden in years to come.

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Authors and Affiliations

  1. Division of Neurosurgery, Department of Pediatric Surgery, McGill University, Montreal Children’s Hospital, Montreal, QC, Canada

    Jean-Pierre Farmer & Roy Dudley

  2. Division of Neurosurgery, Children’s Hospital of Colorado, University of Colorado, Aurora, CO, USA

    Todd Hankinson

Authors
  1. Jean-Pierre Farmer
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  2. Todd Hankinson
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  3. Roy Dudley
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Corresponding author

Correspondence to Jean-Pierre Farmer .

Editor information

Editors and Affiliations

  1. International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. Oakland Medical Center, Oakland, CA, USA

    Dachling Pang

  3. University of Toronto Hospital for Sick Children, Toronto, ON, Canada

    James T. Rutka

Section Editor information

  1. The Hospital for Sick Children, Toronto, ON, Canada

    James T Rutka

  2. Division of Neurosurgery, Hospital for Sick Children, Program in Neuroscience and Mental Health, Hospital for Sick Children Research Institute, University of Toronto, Toronto, ON, Canada

    James T Rutka

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Farmer, JP., Hankinson, T., Dudley, R. (2019). Craniopharyngioma. In: Di Rocco, C., Pang, D., Rutka, J. (eds) Textbook of Pediatric Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-31512-6_87-1

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  • DOI: https://doi.org/10.1007/978-3-319-31512-6_87-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31512-6

  • Online ISBN: 978-3-319-31512-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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