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Caudal Agenesis and Associated Spinal Cord Malformations

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Textbook of Pediatric Neurosurgery

Abstract

Caudal agenesis is a congenital spinal disorder that mainly involves the lower sacral and coccygeal segments. The minimum feature of the disease is a bone anomaly, but it may involve neural components that extend to the low thoracic level. Furthermore, the entity may be associated with various complex congenital syndromes that affect multiple systems, such as the urogenital and anorectal organs. The wide spectrum of phenotypes in caudal agenesis is largely explained by the complex embryological events surrounding secondary neurulation, which not only form the caudal end of the neural tube and caudal vertebral column but also affect the adjacent urogenital and alimentary structures.

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Author information

Authors and Affiliations

  1. Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea

    Ji Yeoun Lee

  2. Division of Pediatric Neurosurgery, Seoul National University Children’s Hospital, 101 Daehak-ro, Jongno-gu, 03080, Seoul, Republic of Korea

    Ji Yeoun Lee & Kyu-Chang Wang

  3. University of California, Davis, Davis, CA, USA

    Dachling Pang

  4. Kaiser Permanente Hospitals of Northern California, Oakland, CA, USA

    Dachling Pang

  5. Great Ormond Street Hospital for Children, NHS Trust, London, UK

    Dachling Pang

Authors
  1. Ji Yeoun Lee
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  2. Dachling Pang
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  3. Kyu-Chang Wang
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Corresponding author

Correspondence to Kyu-Chang Wang .

Editor information

Editors and Affiliations

  1. International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. Oakland Medical Center, Oakland, California, USA

    Dachling Pang

  3. University of Toronto Hospital for Sick Children, Toronto, Ontario, Canada

    James T. Rutka

Section Editor information

  1. Davis; and Kaiser Permanente Hospitals of Northern California, University of California, Oakland, United States of America

    Dachling Pang

  2. Seoul National University, Seoul, Republic of Korea

    Kyu-Chang Wang

  3. Institute of Child Health, University College London, London, UK

    Dominic Thompson

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© 2017 Springer International Publishing AG

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Lee, J.Y., Pang, D., Wang, KC. (2017). Caudal Agenesis and Associated Spinal Cord Malformations. In: Di Rocco, C., Pang, D., Rutka, J. (eds) Textbook of Pediatric Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-31512-6_119-1

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  • DOI: https://doi.org/10.1007/978-3-319-31512-6_119-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31512-6

  • Online ISBN: 978-3-319-31512-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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