Definition
A clinicopathologic entity characterized by a tumor-like deposition of calcium without an obvious associated metabolic calcium disorder.
Clinical Features
Incidence
Very rare with more prevalence in Africans and African-Americans ethnic groups (Czerniak 2016).
Age
It typically occurs in healthy children, adolescents, and young adults.
Sex
No sex predilection is apparently reported (Bertoni et al. 1990; Olsen and Chew 2006).
Site
Periarticular soft tissue in the vicinity of major joints, such as hips, shoulders, knees, and posterior elbows, rare cases localized in the spine, in the hands and feet, and in the temporomandibular joint has been reported (Czerniak 2016; Bertoni et al. 1990; Olsen and Chew 2006). Bilateral symmetric involvement of...
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References and Further Reading
Bertoni, F., Unni, K. K., Dahlin, D. C., Beabout, J. W., & Onofrio, B. M. (1990). Calcifying pseudoneoplasms of the neural axis. Journal of Neurosurgery, 72(1), 42–48.
Czerniak, B. (Ed.). (2016). Dorfman and Czerniak’s: Bone tumors (2nd ed.). Philadelphia: Elsevier Saunders.
Olsen, K. M., & Chew, F. S. (2006). Tumoral calcinosis: Pearls, polemics, and alternative possibilities. Radiographics, 26(3), 871–885.
Slavin, R. E., Wen, J., Kumar, D., & Evans, E. B. (1993). Familial tumoral calcinosis. A clinical, histopathologic, and ultrastructural study with an analysis of its calcifying process and pathogenesis. The American Journal of Surgical Pathology, 17(8), 788–802.
Steinbach, L. S., Johnston, J. O., Tepper, E. F., Honda, G. D., & Martel, W. (1995). Tumoral calcinosis: Radiologic-pathologic correlation. Skeletal Radiology, 24(8), 573–578.
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Alberto, R. (2020). Tumoral Calcinosis. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5473-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_5473-1
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