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Encyclopedia of Pathology pp 1–3Cite as

Myolipoma

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Extrauterine lipoleiomyoma

Definition

Myolipoma is a benign lipomatous tumor composed of mature adipose tissue and well-differentiated smooth muscle cells.

Clinical Features

  • Incidence

    Myolipomas are rare with less than 100 cases reported in the literature (Meis and Enzinger 1991; Fukushima et al. 2017).

  • Age

    The median age is approximately 55 years with a relatively broad range (28–94 years) (Meis and Enzinger 1991; Fukushima et al. 2017).

  • Sex

    Females are predominantly affected (F:M approximately 15:1) (Meis and Enzinger 1991; Fukushima et al. 2017).

  • Site

    Myolipomas typically present as a deep-seated mass in the retroperitoneum, abdominal cavity, or pelvis (Meis and Enzinger 1991; Fukushima et al. 2017).

  • Treatment

    Complete excision is curative.

  • Outcome

    These are benign neoplasms with no recurrences reported following complete surgical excision.

Macroscopy

Gross examination reveals a well-circumscribed lobulated or nodular mass generally surrounded by a thin capsule. Deep-seated...

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References and Further Reading

  • Fukushima, M., Schaefer, I. M., & Fletcher, C. D. (2017). Myolipoma of soft tissue: Clinicopathologic analysis of 34 cases. The American Journal of Surgical Pathology, 41(2), 153–160.

    Article  Google Scholar 

  • Hisaoka, M., Sheng, W. Q., Tanaka, A., et al. (2002). HMGIC alterations in smooth muscle tumors of soft tissue and other sites. Cancer Genetics and Cytogenetics, 138(1), 50–55.

    Article  CAS  Google Scholar 

  • Meis, J. M., & Enzinger, F. M. (1991). Myolipoma of soft tissue. The American Journal of Surgical Pathology, 15(2), 121–125.

    Article  CAS  Google Scholar 

  • Panagopoulos, I., Gorunova, L., Agostini, A., et al. (2016). Fusion of the HMGA2 and C9orf92 genes in myolipoma with t(9;12)(p22q14). Diagnostic Pathology, 11, 22.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Mayo Clinic, Rochester, MN, USA

    Karen Fritchie

Authors
  1. Karen Fritchie
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Corresponding author

Correspondence to Karen Fritchie .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Cite this entry

Fritchie, K. (2020). Myolipoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5433-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5433-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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