Clinical Features
Incidence
CL is extremely rare, with only few small series and single cases reported.
Age
It occurs over a wide age range, but predominately in young adults, with a median of 30 years (Thway et al. 2012).
Sex
CL arises more frequently in women (Thway et al. 2012).
Site
Tumors are more frequently deep-seated and involve the proximal extremities and limb girdles. CL may also occur in the head and neck, particularly in the oral cavity (Meis and Enzinger 1993; Thway et al. 2012).
Treatment
Surgical excision is the primary treatment for eradication of the tumor.
Outcome
CL is benign and complete surgical removal is curative.
Macroscopy
CL appears as a well-circumscribed mass, measuring in average 4–5 cm (range 2–11), with a lobulated yellow cut surface and gelatinous tan-gray areas (Thway et al. 2012). Hemorrhage can...
References
Ballaux, F., Debiec-Rychter, M., De Wever, I., & Sciot, R. (2004). Chondroid lipoma is characterized by t(11;16)(q13;p12–13). Virchows Archiv, 444(2), 208–210.
Flucke, U., Tops, B. B., de Saint Aubain Somerhausen, N., Bras, J., Creytens, D. H., Küsters, B., Groenen, P. J., Verdijk, M. A., Suurmeijer, A. J., & Mentzel, T. (2013). Presence of C11orf95-MKL2 fusion is a consistent finding in chondroid lipomas: a study of eight cases. Histopathology, 62, 925–930.
Gisselsson, D., Domanski, H. A., Höglund, M., Carlén, B., Mertens, F., Willén, H., & Mandahl, N. (1999). Unique cytological features and chromosome aberrations in chondroid lipoma: A case report based on fine-needle aspiration cytology, histopathology, electron microscopy, chromosome banding, and molecular cytogenetics. The American Journal of Surgical Pathology, 23, 1300–1304.
Huang, D., Sumegi, J., Dal Cin, P., Reith, J. D., Yasuda, T., Nelson, M., Muirhead, D., & Bridge, J. A. (2010). C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma. Genes, Chromosomes & Cancer, 49, 810–818.
Meis, J. M., & Enzinger, F. M. (1993). Chondroid lipoma: a unique tumor simulating liposarcoma and myxoid chondrosarcoma. The American Journal of Surgical Pathology, 17, 1103–1112.
Thway, K., Flora, R. S., & Fisher, C. (2012). Chondroid lipoma: An update and review. Annals of Diagnostic Pathology, 16, 230–234.
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Franchi, A. (2020). Chondroid Lipoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5365-1
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